Artículos

A brain-centric model of suicidal behavior / J. John Mann en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 902-916 Título : A brain-centric model of suicidal behavior Tipo de documento: texto impreso Autores: J. John Mann, Autor ; Mina M. Rizk, Autor Fecha de publicación: 2020 Artículo en la página: pp. 902-916 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Suicidio, Prevención del suicidio, Modelo de estrés-diátesis Resumen: The suicide death toll is alarmingly high, outnumbering deaths from war and homicide worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because it is much more than a response to life stressors. Campaigns to lower U.S. suicide rates by 20% by 2025, and even to zero, confront hard realities such as not knowing why the annual suicide rate in the United States has risen every year since 2000 (2). Link: ./index.php?lvl=notice_display&id=25584 [artículo] A brain-centric model of suicidal behavior [texto impreso] / J. John Mann, Autor ; Mina M. Rizk, Autor . - 2020 . - pp. 902-916. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 902-916 Palabras clave: Suicidio, Prevención del suicidio, Modelo de estrés-diátesis Resumen: The suicide death toll is alarmingly high, outnumbering deaths from war and homicide worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because it is much more than a response to life stressors. Campaigns to lower U.S. suicide rates by 20% by 2025, and even to zero, confront hard realities such as not knowing why the annual suicide rate in the United States has risen every year since 2000 (2). Link: ./index.php?lvl=notice_display&id=25584

Genome-wide association study of suicide death and polygenic prediction of clinical antecedents / Anna R. Docherty en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 917-927 Título : Genome-wide association study of suicide death and polygenic prediction of clinical antecedents Tipo de documento: texto impreso Autores: Anna R. Docherty, Autor ; Andrey A. Shabalin, Autor ; Emily DiBlasi, Autor Fecha de publicación: 2020 Artículo en la página: pp. 917-927 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: GWAS, Suicidio, Puntaje poligénico Resumen: Death by suicide is a highly preventable yet growing worldwide health crisis. To date, there has been a lack of adequately powered genomic studies of suicide, with no sizable suicide death cohorts available for analysis. To address this limitation, the authors conducted the first comprehensive genomic analysis of suicide death using previously unpublished genotype data from a large population-ascertained cohort. Link: ./index.php?lvl=notice_display&id=25586 [artículo] Genome-wide association study of suicide death and polygenic prediction of clinical antecedents [texto impreso] / Anna R. Docherty, Autor ; Andrey A. Shabalin, Autor ; Emily DiBlasi, Autor . - 2020 . - pp. 917-927. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 917-927 Palabras clave: GWAS, Suicidio, Puntaje poligénico Resumen: Death by suicide is a highly preventable yet growing worldwide health crisis. To date, there has been a lack of adequately powered genomic studies of suicide, with no sizable suicide death cohorts available for analysis. To address this limitation, the authors conducted the first comprehensive genomic analysis of suicide death using previously unpublished genotype data from a large population-ascertained cohort. Link: ./index.php?lvl=notice_display&id=25586

The sources of parent-child transmission of risk for suicide attempt and deaths by suicide in swedish national samples / Kenneth S. Kendler en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 928-935 Título : The sources of parent-child transmission of risk for suicide attempt and deaths by suicide in swedish national samples Tipo de documento: texto impreso Autores: Kenneth S. Kendler, Autor ; Henrik Ohlsson, Autor ; Jan Sundquist, Autor Fecha de publicación: 2020 Artículo en la página: pp. 928-935 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Comportamiento suicida, Genética, Infancia Resumen: The authors aimed to clarify the sources of parent-child transmission for suicide attempt and death by suicide. Three sources of parent-child resemblance (genes plus rearing, genes only, and rearing only) were examined in parents and offspring from four family types from Swedish national samples: intact nuclear families, families with a not-lived-with biological father, families with a stepfather,... Link: ./index.php?lvl=notice_display&id=25587 [artículo] The sources of parent-child transmission of risk for suicide attempt and deaths by suicide in swedish national samples [texto impreso] / Kenneth S. Kendler, Autor ; Henrik Ohlsson, Autor ; Jan Sundquist, Autor . - 2020 . - pp. 928-935. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 928-935 Palabras clave: Comportamiento suicida, Genética, Infancia Resumen: The authors aimed to clarify the sources of parent-child transmission for suicide attempt and death by suicide. Three sources of parent-child resemblance (genes plus rearing, genes only, and rearing only) were examined in parents and offspring from four family types from Swedish national samples: intact nuclear families, families with a not-lived-with biological father, families with a stepfather,... Link: ./index.php?lvl=notice_display&id=25587

Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life / Katherine L. Musliner en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 936-943 Título : Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life Tipo de documento: texto impreso Autores: Katherine L. Musliner, Autor ; Morten D. Krebs, Autor ; Clara Albiñana, Autor Fecha de publicación: 2020 Artículo en la página: pp. 936-943 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos depresivos, Trastornos bipolares y relacionados, Psicosis, Genética / Genómica Resumen: The authors investigated the associations between polygenic liability and progression to bipolar disorder or psychotic disorders among individuals diagnosed with unipolar depression in early life. Link: ./index.php?lvl=notice_display&id=25588 [artículo] Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life [texto impreso] / Katherine L. Musliner, Autor ; Morten D. Krebs, Autor ; Clara Albiñana, Autor . - 2020 . - pp. 936-943. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 936-943 Palabras clave: Trastornos depresivos, Trastornos bipolares y relacionados, Psicosis, Genética / Genómica Resumen: The authors investigated the associations between polygenic liability and progression to bipolar disorder or psychotic disorders among individuals diagnosed with unipolar depression in early life. Link: ./index.php?lvl=notice_display&id=25588

An exposure-wide and mendelian randomization approach to identifying modifiable factors for the prevention of depression / Karmel W. Choi en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 944-954 Título : An exposure-wide and mendelian randomization approach to identifying modifiable factors for the prevention of depression Tipo de documento: texto impreso Autores: Karmel W. Choi, Autor ; Murray B. Stein, Autor ; Kristen M. Nishimi, Autor Fecha de publicación: 2020 Artículo en la página: pp. 944-954 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Depresión, Prevención, Aleatorización mendeliana, Factores protectores, Riesgo poligénico, Exposoma Resumen: Efforts to prevent depression, the leading cause of disability worldwide, have focused on a limited number of candidate factors. Using phenotypic and genomic data from over 100,000 UK Biobank participants, the authors sought to systematically screen and validate a wide range of potential modifiable factors for depression. Link: ./index.php?lvl=notice_display&id=25589 [artículo] An exposure-wide and mendelian randomization approach to identifying modifiable factors for the prevention of depression [texto impreso] / Karmel W. Choi, Autor ; Murray B. Stein, Autor ; Kristen M. Nishimi, Autor . - 2020 . - pp. 944-954. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 944-954 Palabras clave: Depresión, Prevención, Aleatorización mendeliana, Factores protectores, Riesgo poligénico, Exposoma Resumen: Efforts to prevent depression, the leading cause of disability worldwide, have focused on a limited number of candidate factors. Using phenotypic and genomic data from over 100,000 UK Biobank participants, the authors sought to systematically screen and validate a wide range of potential modifiable factors for depression. Link: ./index.php?lvl=notice_display&id=25589

Well-being, burnout, and depression among north american psychiatrists / Richard F. Summers en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 955-964 Título : Well-being, burnout, and depression among north american psychiatrists : the state of our profession Tipo de documento: texto impreso Autores: Richard F. Summers, Autor ; Tristan Gorrindo, Autor ; Seungyoung Hwang, Autor Fecha de publicación: 2020 Artículo en la página: pp. 955-964 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Otros problemas profesionales, Trastornos depresivos Resumen: The authors examined the prevalence of burnout and depressive symptoms among North American psychiatrists, determined demographic and practice characteristics that increase the risk for these symptoms, and assessed the correlation between burnout and depression. Link: ./index.php?lvl=notice_display&id=25590 [artículo] Well-being, burnout, and depression among north american psychiatrists : the state of our profession [texto impreso] / Richard F. Summers, Autor ; Tristan Gorrindo, Autor ; Seungyoung Hwang, Autor . - 2020 . - pp. 955-964. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 955-964 Palabras clave: Otros problemas profesionales, Trastornos depresivos Resumen: The authors examined the prevalence of burnout and depressive symptoms among North American psychiatrists, determined demographic and practice characteristics that increase the risk for these symptoms, and assessed the correlation between burnout and depression. Link: ./index.php?lvl=notice_display&id=25590

Low-dose testosterone augmentation for antidepressant-resistant major depressive disorder in women / Laura E. Dichtel en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 965-973 Título : Low-dose testosterone augmentation for antidepressant-resistant major depressive disorder in women : an 8-week randomized placebo-controlled study Tipo de documento: texto impreso Autores: Laura E. Dichtel, Autor ; Linda L. Carpenter, Autor ; Maren Nyer, Autor Fecha de publicación: 2020 Artículo en la página: pp. 965-973 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Testosterona, Aumento, Depresión resistente a los antidepresivos, Trastorno depresivo mayor, Efecto placebo Resumen: Low-dose testosterone has been shown to improve depression symptom severity, fatigue, and sexual function in small studies in women not formally diagnosed with major depressive disorder. The authors sought to determine whether adjunctive low-dose transdermal testosterone improves depression symptom severity, fatigue, and sexual function in women with antidepressant-resistant major depression. Link: ./index.php?lvl=notice_display&id=25591 [artículo] Low-dose testosterone augmentation for antidepressant-resistant major depressive disorder in women : an 8-week randomized placebo-controlled study [texto impreso] / Laura E. Dichtel, Autor ; Linda L. Carpenter, Autor ; Maren Nyer, Autor . - 2020 . - pp. 965-973. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 965-973 Palabras clave: Testosterona, Aumento, Depresión resistente a los antidepresivos, Trastorno depresivo mayor, Efecto placebo Resumen: Low-dose testosterone has been shown to improve depression symptom severity, fatigue, and sexual function in small studies in women not formally diagnosed with major depressive disorder. The authors sought to determine whether adjunctive low-dose transdermal testosterone improves depression symptom severity, fatigue, and sexual function in women with antidepressant-resistant major depression. Link: ./index.php?lvl=notice_display&id=25591

Identification of a signaling mechanism by which the microbiome regulates th17 cell-mediated depressive-like behaviors in mice / Eva M. Medina-Rodriguez en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No. 10 (Octubre)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 974-990 Título : Identification of a signaling mechanism by which the microbiome regulates th17 cell-mediated depressive-like behaviors in mice Tipo de documento: texto impreso Autores: Eva M. Medina-Rodriguez, Autor ; Derik Madorma, Autor ; Gregory O’Connor, Autor Fecha de publicación: 2020 Artículo en la página: pp. 974-990 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Microbioma, Depresión, Células Th17, Autoinductor-2 Resumen: Microbiota dysbiosis has been linked to major depressive disorder, but the mechanisms whereby the microbiota modulates mood remain poorly understood. The authors tested whether specific changes in the microbiome modulate depressive-like behaviors. Link: ./index.php?lvl=notice_display&id=25592 [artículo] Identification of a signaling mechanism by which the microbiome regulates th17 cell-mediated depressive-like behaviors in mice [texto impreso] / Eva M. Medina-Rodriguez, Autor ; Derik Madorma, Autor ; Gregory O’Connor, Autor . - 2020 . - pp. 974-990. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No. 10 (Octubre) . - pp. 974-990 Palabras clave: Microbioma, Depresión, Células Th17, Autoinductor-2 Resumen: Microbiota dysbiosis has been linked to major depressive disorder, but the mechanisms whereby the microbiota modulates mood remain poorly understood. The authors tested whether specific changes in the microbiome modulate depressive-like behaviors. Link: ./index.php?lvl=notice_display&id=25592