Artículos

The state of our understanding of the pathophysiology and optimal treatment of depression / Charles B. Nemeroff en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 671-685 Título : The state of our understanding of the pathophysiology and optimal treatment of depression : glass half full or half empty? Tipo de documento: texto impreso Autores: Charles B. Nemeroff, Autor Fecha de publicación: 2021 Artículo en la página: pp. 671-685 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno depresivo mayor, Etiología, Investigación, Tratamiento Resumen: Major depressive disorder is a remarkably common and often severe psychiatric disorder associated with high levels of morbidity and mortality. Patients with major depression are prone to several comorbid psychiatric conditions, including posttraumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and substance use disorders, and medical conditions, including cardiovascular disease, diabetes, stroke, cancer, which, coupled with the risk of suicide, result in a shortened life expectancy. Link: ./index.php?lvl=notice_display&id=25874 [artículo] The state of our understanding of the pathophysiology and optimal treatment of depression : glass half full or half empty? [texto impreso] / Charles B. Nemeroff, Autor . - 2021 . - pp. 671-685. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 671-685 Palabras clave: Trastorno depresivo mayor, Etiología, Investigación, Tratamiento Resumen: Major depressive disorder is a remarkably common and often severe psychiatric disorder associated with high levels of morbidity and mortality. Patients with major depression are prone to several comorbid psychiatric conditions, including posttraumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and substance use disorders, and medical conditions, including cardiovascular disease, diabetes, stroke, cancer, which, coupled with the risk of suicide, result in a shortened life expectancy. Link: ./index.php?lvl=notice_display&id=25874

Hormonal treatments for major depressive disorder / Jennifer B. Dwyer en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 686-705 Título : Hormonal treatments for major depressive disorder : state of the art Tipo de documento: texto impreso Autores: Jennifer B. Dwyer, Autor ; Awais Aftab, Autor ; Rajiv Radhakrishnan, Autor Fecha de publicación: 2021 Artículo en la página: pp. 686-705 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antidepresivos, Neuroendocrinología Resumen: Major depressive disorder is a common psychiatric disorder associated with marked suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030, major depression will be the leading cause of disease burden worldwide. While numerous treatments for major depression exist, many patients do not respond adequately to traditional antidepressants. Link: ./index.php?lvl=notice_display&id=25875 [artículo] Hormonal treatments for major depressive disorder : state of the art [texto impreso] / Jennifer B. Dwyer, Autor ; Awais Aftab, Autor ; Rajiv Radhakrishnan, Autor . - 2021 . - pp. 686-705. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 686-705 Palabras clave: Antidepresivos, Neuroendocrinología Resumen: Major depressive disorder is a common psychiatric disorder associated with marked suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030, major depression will be the leading cause of disease burden worldwide. While numerous treatments for major depression exist, many patients do not respond adequately to traditional antidepressants. Link: ./index.php?lvl=notice_display&id=25875

20-year trends in the pharmacologic treatment of bipolar disorder by psychiatrists in outpatient care settings / Taeho Greg Rhee en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 706-715 Título : 20-year trends in the pharmacologic treatment of bipolar disorder by psychiatrists in outpatient care settings Tipo de documento: texto impreso Autores: Taeho Greg Rhee, Autor ; Mark Olfson, Autor ; Andrew A. Nierenberg, Autor Fecha de publicación: 2021 Artículo en la página: pp. 706-715 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno bipolar, Litio, Antipsicóticos, Paciente externo Resumen: Pharmacological options for treating bipolar disorder have increased over the past 20 years, with several second-generation antipsychotics receiving regulatory approval in the 1990s. The authors describe trends in use of pharmacological agents in the outpatient management of bipolar disorder. Link: ./index.php?lvl=notice_display&id=25876 [artículo] 20-year trends in the pharmacologic treatment of bipolar disorder by psychiatrists in outpatient care settings [texto impreso] / Taeho Greg Rhee, Autor ; Mark Olfson, Autor ; Andrew A. Nierenberg, Autor . - 2021 . - pp. 706-715. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 706-715 Palabras clave: Trastorno bipolar, Litio, Antipsicóticos, Paciente externo Resumen: Pharmacological options for treating bipolar disorder have increased over the past 20 years, with several second-generation antipsychotics receiving regulatory approval in the 1990s. The authors describe trends in use of pharmacological agents in the outpatient management of bipolar disorder. Link: ./index.php?lvl=notice_display&id=25876

Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression / Eleanor J. Cole en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 716-726 Título : Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression Tipo de documento: texto impreso Autores: Eleanor J. Cole, Autor ; Katy H. Stimpson, Autor ; Brandon S. Bentzley, Autor Fecha de publicación: 2021 Artículo en la página: pp. 716-726 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulación magnética transcraneal repetitiva, Estimulación Theta-Burst intermitente, Depresión Resistente al tratamiento, Conectividad funcional, Medicina de Precisión, Estimulación cerebral dirigida Resumen: New antidepressant treatments are needed that are effective, rapid acting, safe, and tolerable. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation treatment that has been approved by the U.S. Food and Drug Administration for treatment-resistant depression. Link: ./index.php?lvl=notice_display&id=25877 [artículo] Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression [texto impreso] / Eleanor J. Cole, Autor ; Katy H. Stimpson, Autor ; Brandon S. Bentzley, Autor . - 2021 . - pp. 716-726. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 716-726 Palabras clave: Estimulación magnética transcraneal repetitiva, Estimulación Theta-Burst intermitente, Depresión Resistente al tratamiento, Conectividad funcional, Medicina de Precisión, Estimulación cerebral dirigida Resumen: New antidepressant treatments are needed that are effective, rapid acting, safe, and tolerable. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation treatment that has been approved by the U.S. Food and Drug Administration for treatment-resistant depression. Link: ./index.php?lvl=notice_display&id=25877

Reduction in mental health treatment utilization among transgender individuals after gender-affirming surgeries / Richard Bränström en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 177-727 Título : Reduction in mental health treatment utilization among transgender individuals after gender-affirming surgeries : a total population study Tipo de documento: texto impreso Autores: Richard Bränström, Autor ; John E. Pachankis, Autor Fecha de publicación: 2021 Artículo en la página: pp. 177-727 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ansiedad, Suicidio, Transgénero, Incongruencia de género, Tratamientos que afirman el género Resumen: Despite professional recommendations to consider gender-affirming hormone and surgical interventions for transgender individuals experiencing gender incongruence, the long-term effect of such interventions on mental health is largely unknown. Link: ./index.php?lvl=notice_display&id=25878 [artículo] Reduction in mental health treatment utilization among transgender individuals after gender-affirming surgeries : a total population study [texto impreso] / Richard Bränström, Autor ; John E. Pachankis, Autor . - 2021 . - pp. 177-727. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 177-727 Palabras clave: Ansiedad, Suicidio, Transgénero, Incongruencia de género, Tratamientos que afirman el género Resumen: Despite professional recommendations to consider gender-affirming hormone and surgical interventions for transgender individuals experiencing gender incongruence, the long-term effect of such interventions on mental health is largely unknown. Link: ./index.php?lvl=notice_display&id=25878

Association between ambient air pollution and daily hospital admissions for depression in 75 chinese cities / Xuelin Gu en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 735-743 Título : Association between ambient air pollution and daily hospital admissions for depression in 75 chinese cities Tipo de documento: texto impreso Autores: Xuelin Gu, Autor ; Tongjun Guo, Autor ; Yaqin Si, Autor Fecha de publicación: 2021 Artículo en la página: pp. 735-743 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Epidemiología, Depresión, Contaminación del aire, Materia particular Resumen: Although the association between ambient air pollution and risk of depression has been investigated in several epidemiological studies, the evidence is still lacking for hospital admissions for depression, which indicates a more severe form of depressive episode. Link: ./index.php?lvl=notice_display&id=25879 [artículo] Association between ambient air pollution and daily hospital admissions for depression in 75 chinese cities [texto impreso] / Xuelin Gu, Autor ; Tongjun Guo, Autor ; Yaqin Si, Autor . - 2021 . - pp. 735-743. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 735-743 Palabras clave: Epidemiología, Depresión, Contaminación del aire, Materia particular Resumen: Although the association between ambient air pollution and risk of depression has been investigated in several epidemiological studies, the evidence is still lacking for hospital admissions for depression, which indicates a more severe form of depressive episode. Link: ./index.php?lvl=notice_display&id=25879

Intergenerational effects of maternal holocaust exposure on fkbp5 methylation / Linda M. Bierer en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 744-753 Título : Intergenerational effects of maternal holocaust exposure on fkbp5 methylation Tipo de documento: texto impreso Autores: Linda M. Bierer, Autor ; Heather N. Bader, Autor ; Nikolaos P. Daskalakis, Autor Fecha de publicación: 2021 Artículo en la página: pp. 744-753 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Epigenética, Estrés, Trauma intergeneracional, FKBP5, Holocausto, Programación de desarrollo Resumen: There is growing evidence that exposure to trauma prior to conception can affect offspring. The authors have reported that adult offspring of Holocaust survivors showed lower methylation of FK506 binding protein 5 (FKBP5) intron 7, site 6 compared with Jewish comparison volunteers. Link: ./index.php?lvl=notice_display&id=25880 [artículo] Intergenerational effects of maternal holocaust exposure on fkbp5 methylation [texto impreso] / Linda M. Bierer, Autor ; Heather N. Bader, Autor ; Nikolaos P. Daskalakis, Autor . - 2021 . - pp. 744-753. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 744-753 Palabras clave: Epigenética, Estrés, Trauma intergeneracional, FKBP5, Holocausto, Programación de desarrollo Resumen: There is growing evidence that exposure to trauma prior to conception can affect offspring. The authors have reported that adult offspring of Holocaust survivors showed lower methylation of FK506 binding protein 5 (FKBP5) intron 7, site 6 compared with Jewish comparison volunteers. Link: ./index.php?lvl=notice_display&id=25880

Brain reward system dysfunction in adolescence / Brent I. Rappaport en The American Journal of Psychiatry, Año 2020 - Vol. 177 - No.8 (Agosto)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 754-763 Título : Brain reward system dysfunction in adolescence : current, cumulative, and developmental periods of depression Tipo de documento: texto impreso Autores: Brent I. Rappaport, Autor ; Sridhar Kandala, Autor ; Joan L. Luby, Autor Fecha de publicación: 2021 Artículo en la página: pp. 754-763 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Adolescentes, Depresión, Infancia, Preescolar, Recompensa, Anticipación, Período de desarrollo. Resumen: Reward system dysfunction is a well-known correlate and predictor of depression in adults and adolescents, with depressed individuals showing blunted (hyporeactive) striatal response to monetary rewards. Furthermore, studies of remitted depression suggest network-wide hyporeactivity of striatal (caudate, putamen, nucleus accumbens) and cortical (insula, anterior cingulate cortex [ACC]) regions even in the absence of current symptoms. Link: ./index.php?lvl=notice_display&id=25881 [artículo] Brain reward system dysfunction in adolescence : current, cumulative, and developmental periods of depression [texto impreso] / Brent I. Rappaport, Autor ; Sridhar Kandala, Autor ; Joan L. Luby, Autor . - 2021 . - pp. 754-763. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2020 - Vol. 177 - No.8 (Agosto) . - pp. 754-763 Palabras clave: Adolescentes, Depresión, Infancia, Preescolar, Recompensa, Anticipación, Período de desarrollo. Resumen: Reward system dysfunction is a well-known correlate and predictor of depression in adults and adolescents, with depressed individuals showing blunted (hyporeactive) striatal response to monetary rewards. Furthermore, studies of remitted depression suggest network-wide hyporeactivity of striatal (caudate, putamen, nucleus accumbens) and cortical (insula, anterior cingulate cortex [ACC]) regions even in the absence of current symptoms. Link: ./index.php?lvl=notice_display&id=25881