Biblioteca Humberto Rosselli Quijano
European Neuropsychopharmacology / European College of Neuropsychopharmacology (ECNP) (1990; Netherlands, Paises Bajos) . Año 2015 - Vol. 25 - No.3Mención de fecha: Marzo Fecha de aparición: 23/08/2021 |
[número]
es un número de European Neuropsychopharmacology / European College of Neuropsychopharmacology (ECNP) (1990; Netherlands, Paises Bajos)
[número] es un número de European Neuropsychopharmacology / European College of Neuropsychopharmacology (ECNP) (1990; Netherlands, Paises Bajos) Idioma : Inglés (eng) Idioma original : Inglés (eng)
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Ejemplares (1)
Código de barras | Signatura | Tipo de medio | Ubicación | Sección | Estado |
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101045 | European Neuropsychopharmacology | Publicaciones seriadas | Biblioteca Instituto Colombiano del Sistema Nervioso | Hemeroteca | Disponible |
Artículos
Añadir el resultado a su cestaToward stratified treatments for bipolar disorders / Gregor Hasler en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Toward stratified treatments for bipolar disorders Tipo de documento: texto impreso Autores: Gregor Hasler, Autor ; Andreas Wolf, Autor Fecha de publicación: 2021 Artículo en la página: pp. 283-294 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno bipolar, Medicina estratificada, Medicina personalizada, Medicina de precisión, Optimización del tratamiento Resumen: In bipolar disorders, there are unclear diagnostic boundaries with unipolar depression and schizophrenia, inconsistency of treatment guidelines, relatively long trial-and-error phases of treatment optimization, and increasing use of complex combination therapies lacking empirical evidence. Link: ./index.php?lvl=notice_display&id=26807
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 283-294[artículo] Toward stratified treatments for bipolar disorders [texto impreso] / Gregor Hasler, Autor ; Andreas Wolf, Autor . - 2021 . - pp. 283-294.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 283-294
Palabras clave: Trastorno bipolar, Medicina estratificada, Medicina personalizada, Medicina de precisión, Optimización del tratamiento Resumen: In bipolar disorders, there are unclear diagnostic boundaries with unipolar depression and schizophrenia, inconsistency of treatment guidelines, relatively long trial-and-error phases of treatment optimization, and increasing use of complex combination therapies lacking empirical evidence. Link: ./index.php?lvl=notice_display&id=26807 Effectiveness of different dosing regimens of risperidone and olanzapine in schizophrenia / Hiroyoshi Takeuchi en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Effectiveness of different dosing regimens of risperidone and olanzapine in schizophrenia Tipo de documento: texto impreso Autores: Hiroyoshi Takeuchi, Autor ; Gagan Fervaha, Autor ; Jimmy Lee, Autor Fecha de publicación: 2021 Artículo en la página: pp. 295-302 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Dosificación, Olanzapina, Risperidona, Esquizofrenia Resumen: The objective of this study was to evaluate the effectiveness and impact of once- versus twice-daily dosing of risperidone and olanzapine on clinical outcomes in patients with schizophrenia. Data from phase 1 of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia study were used. Link: ./index.php?lvl=notice_display&id=26808
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 295-302[artículo] Effectiveness of different dosing regimens of risperidone and olanzapine in schizophrenia [texto impreso] / Hiroyoshi Takeuchi, Autor ; Gagan Fervaha, Autor ; Jimmy Lee, Autor . - 2021 . - pp. 295-302.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 295-302
Palabras clave: Antipsicóticos, Dosificación, Olanzapina, Risperidona, Esquizofrenia Resumen: The objective of this study was to evaluate the effectiveness and impact of once- versus twice-daily dosing of risperidone and olanzapine on clinical outcomes in patients with schizophrenia. Data from phase 1 of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia study were used. Link: ./index.php?lvl=notice_display&id=26808 Cardiac effects of sertindole and quetiapine / Jimmi R. Nielsen en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Cardiac effects of sertindole and quetiapine : Analysis of ECGs from a randomized double-blind study in patients with schizophrenia Tipo de documento: texto impreso Autores: Jimmi R. Nielsen, Autor ; Jørgen Matz, Autor ; Aurélia Mittoux, Autor Fecha de publicación: 2021 Artículo en la página: pp. 303-311 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Onda T., Morfología, QT, QTc, SCD Resumen: The QT interval is the most widely used surrogate marker for predicting TdP; however, several alternative surrogate markers, such as Tpeak–Tend (TpTe) and a quantitative T-wave morphology combination score (MCS) have emerged. Link: ./index.php?lvl=notice_display&id=26809
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 303-311[artículo] Cardiac effects of sertindole and quetiapine : Analysis of ECGs from a randomized double-blind study in patients with schizophrenia [texto impreso] / Jimmi R. Nielsen, Autor ; Jørgen Matz, Autor ; Aurélia Mittoux, Autor . - 2021 . - pp. 303-311.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 303-311
Palabras clave: Onda T., Morfología, QT, QTc, SCD Resumen: The QT interval is the most widely used surrogate marker for predicting TdP; however, several alternative surrogate markers, such as Tpeak–Tend (TpTe) and a quantitative T-wave morphology combination score (MCS) have emerged. Link: ./index.php?lvl=notice_display&id=26809 Impact of BPRS interview length on ratings reliability in a schizophrenia trial / Steven David Targum en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
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Título : Impact of BPRS interview length on ratings reliability in a schizophrenia trial Tipo de documento: texto impreso Autores: Steven David Targum, Autor ; Jo Cara Pendergrass, Autor ; Chelsea Toner, Autor Fecha de publicación: 2021 Artículo en la página: pp. 312-318 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ensayos clínicos, BPRS, Duración de la entrevista, Esquizofrenia, Precisión de calificaciones, Fiabilidad Resumen: Signal detection in clinical trials relies on ratings reliability. We conducted a reliability analysis of site-independent rater scores derived from audio-digital recordings of site-based rater interviews of the structured Brief Psychiatric Rating Scale (BPRS) in a schizophrenia study. Link: ./index.php?lvl=notice_display&id=26810
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 312-318[artículo] Impact of BPRS interview length on ratings reliability in a schizophrenia trial [texto impreso] / Steven David Targum, Autor ; Jo Cara Pendergrass, Autor ; Chelsea Toner, Autor . - 2021 . - pp. 312-318.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 312-318
Palabras clave: Ensayos clínicos, BPRS, Duración de la entrevista, Esquizofrenia, Precisión de calificaciones, Fiabilidad Resumen: Signal detection in clinical trials relies on ratings reliability. We conducted a reliability analysis of site-independent rater scores derived from audio-digital recordings of site-based rater interviews of the structured Brief Psychiatric Rating Scale (BPRS) in a schizophrenia study. Link: ./index.php?lvl=notice_display&id=26810 Capillary compared to venous blood sampling in clozapine treatment / Jan P.A.M. Bogers en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
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Título : Capillary compared to venous blood sampling in clozapine treatment : patients׳ and healthcare practitioners׳ experiences with a point-of-care device Tipo de documento: texto impreso Autores: Jan P.A.M. Bogers, Autor ; Hong N. Bui, Autor ; Martien H. Herruer, Autor Fecha de publicación: 2021 Artículo en la página: pp. 319-324 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Dispositivo de punto de atención, Clozapina, Esquizofrenia, Agranulocitosis, Neutropenia, Monitoreo hematológico Resumen: Underuse of the antipsychotic clozapine for schizophrenia is an impediment to improving outcomes for patients. Because of its possible severe side effects, including granulocytopenia or even agranulocytosis, clozapine treatment entails regular WBC monitoring, which can be a major drawback for patients and practitioners. Link: ./index.php?lvl=notice_display&id=26811
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 319-324[artículo] Capillary compared to venous blood sampling in clozapine treatment : patients׳ and healthcare practitioners׳ experiences with a point-of-care device [texto impreso] / Jan P.A.M. Bogers, Autor ; Hong N. Bui, Autor ; Martien H. Herruer, Autor . - 2021 . - pp. 319-324.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 319-324
Palabras clave: Dispositivo de punto de atención, Clozapina, Esquizofrenia, Agranulocitosis, Neutropenia, Monitoreo hematológico Resumen: Underuse of the antipsychotic clozapine for schizophrenia is an impediment to improving outcomes for patients. Because of its possible severe side effects, including granulocytopenia or even agranulocytosis, clozapine treatment entails regular WBC monitoring, which can be a major drawback for patients and practitioners. Link: ./index.php?lvl=notice_display&id=26811 Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition / Chandni Hindocha en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition : A randomised, double-blind, placebo-controlled study in cannabis users Tipo de documento: texto impreso Autores: Chandni Hindocha, Autor ; Tom P. Freeman, Autor ; Gráinne L. Schäfer, Autor Fecha de publicación: 2021 Artículo en la página: pp. 325-334 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Sistema endocannabinoide, Procesamiento emocional, Esquizotipia, A9-tetrahidrocannabinol (THC), Cannabidiol (CBD) Resumen: Acute administration of the primary psychoactive constituent of cannabis, Δ-9-tetrahydrocannabinol (THC), impairs human facial affect recognition, implicating the endocannabinoid system in emotional processing. Another main constituent of cannabis, cannabidiol (CBD), has seemingly opposite functional effects on the brain. Link: ./index.php?lvl=notice_display&id=26812
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 325-334[artículo] Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition : A randomised, double-blind, placebo-controlled study in cannabis users [texto impreso] / Chandni Hindocha, Autor ; Tom P. Freeman, Autor ; Gráinne L. Schäfer, Autor . - 2021 . - pp. 325-334.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 325-334
Palabras clave: Sistema endocannabinoide, Procesamiento emocional, Esquizotipia, A9-tetrahidrocannabinol (THC), Cannabidiol (CBD) Resumen: Acute administration of the primary psychoactive constituent of cannabis, Δ-9-tetrahydrocannabinol (THC), impairs human facial affect recognition, implicating the endocannabinoid system in emotional processing. Another main constituent of cannabis, cannabidiol (CBD), has seemingly opposite functional effects on the brain. Link: ./index.php?lvl=notice_display&id=26812 The pharmacodynamic properties of lurasidone and their role in its antidepressant efficacy in bipolar disorder / Konstantinos N. Fountoulakis en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : The pharmacodynamic properties of lurasidone and their role in its antidepressant efficacy in bipolar disorder Tipo de documento: texto impreso Autores: Konstantinos N. Fountoulakis, Autor ; Maria Gazouli, Autor ; John R. Kelsoe, Autor Fecha de publicación: 2021 Artículo en la página: pp. 335-342 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Lurasidona, Depresión bipolar, Neurobiología, Modelos biologicos, Trastorno bipolar Resumen: The treatment of bipolar depression is one of the most challenging issues in contemporary psychiatry. Currently only quetiapine, the olanzapine–fluoxetine combination and recently lurasidone are officially FDA-approved against this condition. Link: ./index.php?lvl=notice_display&id=26813
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 335-342[artículo] The pharmacodynamic properties of lurasidone and their role in its antidepressant efficacy in bipolar disorder [texto impreso] / Konstantinos N. Fountoulakis, Autor ; Maria Gazouli, Autor ; John R. Kelsoe, Autor . - 2021 . - pp. 335-342.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 335-342
Palabras clave: Lurasidona, Depresión bipolar, Neurobiología, Modelos biologicos, Trastorno bipolar Resumen: The treatment of bipolar depression is one of the most challenging issues in contemporary psychiatry. Currently only quetiapine, the olanzapine–fluoxetine combination and recently lurasidone are officially FDA-approved against this condition. Link: ./index.php?lvl=notice_display&id=26813 Repeated amphetamine administration and long-term effects on 50-kHz ultrasonic vocalizations / Nicola Simola en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Repeated amphetamine administration and long-term effects on 50-kHz ultrasonic vocalizations : Possible relevance to the motivational and dopamine-stimulating properties of the drug Tipo de documento: texto impreso Autores: Nicola Simola, Autor ; Micaela Morelli, Autor Fecha de publicación: 2021 Artículo en la página: pp. 343-355 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Apomorfina, Acondicionamiento, Dopamina, Psicoestimulante, Recompensa, Sensibilización Resumen: Ultrasonic vocalizations (USVs) of 50 kHz are thought to indicate positive affective states in rats, and are increasingly being used to investigate the motivational properties of drugs of abuse. Link: ./index.php?lvl=notice_display&id=26814
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 343-355[artículo] Repeated amphetamine administration and long-term effects on 50-kHz ultrasonic vocalizations : Possible relevance to the motivational and dopamine-stimulating properties of the drug [texto impreso] / Nicola Simola, Autor ; Micaela Morelli, Autor . - 2021 . - pp. 343-355.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 343-355
Palabras clave: Apomorfina, Acondicionamiento, Dopamina, Psicoestimulante, Recompensa, Sensibilización Resumen: Ultrasonic vocalizations (USVs) of 50 kHz are thought to indicate positive affective states in rats, and are increasingly being used to investigate the motivational properties of drugs of abuse. Link: ./index.php?lvl=notice_display&id=26814 Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin–dopamine activity modulator / Noriko Yoshimi en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin–dopamine activity modulator Tipo de documento: texto impreso Autores: Noriko Yoshimi, Autor ; Takashi Futamura, Autor ; Kenji Hashimoto, Autor Fecha de publicación: 2021 Artículo en la página: pp. 356-364 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Fármaco antipsicótico, Brexpiprazol, Dizocilpina, Reconocimiento social, Receptor 5-HT1A Resumen: Cognitive impairment, including impaired social cognition, is largely responsible for the deterioration in social life suffered by patients with psychiatric disorders, such as schizophrenia and major depressive disorder (MDD). Link: ./index.php?lvl=notice_display&id=26816
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 356-364[artículo] Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin–dopamine activity modulator [texto impreso] / Noriko Yoshimi, Autor ; Takashi Futamura, Autor ; Kenji Hashimoto, Autor . - 2021 . - pp. 356-364.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 356-364
Palabras clave: Fármaco antipsicótico, Brexpiprazol, Dizocilpina, Reconocimiento social, Receptor 5-HT1A Resumen: Cognitive impairment, including impaired social cognition, is largely responsible for the deterioration in social life suffered by patients with psychiatric disorders, such as schizophrenia and major depressive disorder (MDD). Link: ./index.php?lvl=notice_display&id=26816 Monoamine transporter and receptor interaction profiles of novel psychoactive substances / Anna Rickli en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Monoamine transporter and receptor interaction profiles of novel psychoactive substances : Para-halogenated amphetamines and pyrovalerone cathinones Tipo de documento: texto impreso Autores: Anna Rickli, Autor ; Marius C. Hoener, Autor ; Matthias E. Liechti, Autor Fecha de publicación: 2021 Artículo en la página: pp. 365-376 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Nuevas sustancias psicoactivas, Catinona, Anfetamina, Dopamina, Serotonina, Transportador Resumen: The pharmacology of novel psychoactive substances is mostly unknown. We evaluated the transporter and receptor interaction profiles of a series of para-(4)-substituted amphetamines and pyrovalerone cathinones. Link: ./index.php?lvl=notice_display&id=26817
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 365-376[artículo] Monoamine transporter and receptor interaction profiles of novel psychoactive substances : Para-halogenated amphetamines and pyrovalerone cathinones [texto impreso] / Anna Rickli, Autor ; Marius C. Hoener, Autor ; Matthias E. Liechti, Autor . - 2021 . - pp. 365-376.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 365-376
Palabras clave: Nuevas sustancias psicoactivas, Catinona, Anfetamina, Dopamina, Serotonina, Transportador Resumen: The pharmacology of novel psychoactive substances is mostly unknown. We evaluated the transporter and receptor interaction profiles of a series of para-(4)-substituted amphetamines and pyrovalerone cathinones. Link: ./index.php?lvl=notice_display&id=26817 A pharmacokinetic/pharmacodynamic investigation / William B. Kielbasa en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : A pharmacokinetic/pharmacodynamic investigation : Assessment of edivoxetine and atomoxetine on systemic and central 3,4-dihydroxyphenylglycol, a biochemical marker for norepinephrine transporter inhibition Tipo de documento: texto impreso Autores: William B. Kielbasa, Autor ; Alan Pan, Autor ; Alvaro Pereira, Autor Fecha de publicación: 2021 Artículo en la página: pp. 377-385 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Edivoxetina, DHPG, Farmacocinética, Farmacodinamia, Atomoxetina Resumen: Inhibition of norepinephrine (NE) reuptake into noradrenergic nerves is a common therapeutic target in the central nervous system (CNS). In noradrenergic nerves, NE is oxidized by monoamine oxidase to 3,4-dihydroxyphenylglycol (DHPG). Link: ./index.php?lvl=notice_display&id=26818
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 377-385[artículo] A pharmacokinetic/pharmacodynamic investigation : Assessment of edivoxetine and atomoxetine on systemic and central 3,4-dihydroxyphenylglycol, a biochemical marker for norepinephrine transporter inhibition [texto impreso] / William B. Kielbasa, Autor ; Alan Pan, Autor ; Alvaro Pereira, Autor . - 2021 . - pp. 377-385.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 377-385
Palabras clave: Edivoxetina, DHPG, Farmacocinética, Farmacodinamia, Atomoxetina Resumen: Inhibition of norepinephrine (NE) reuptake into noradrenergic nerves is a common therapeutic target in the central nervous system (CNS). In noradrenergic nerves, NE is oxidized by monoamine oxidase to 3,4-dihydroxyphenylglycol (DHPG). Link: ./index.php?lvl=notice_display&id=26818 Increasing progranulin levels and blockade of the ERK1/2 pathway / Carolina Alquezar en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Increasing progranulin levels and blockade of the ERK1/2 pathway : Upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia Tipo de documento: texto impreso Autores: Carolina Alquezar, Autor ; Noemí Esteras, Autor ; Ana De La Encarnación, Autor Fecha de publicación: 2021 Artículo en la página: pp. 386-403 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: FTLD-TDP, Linfocitos, Proliferación celular, Progranulina, ERK1 / 2, CDK6 Resumen: Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder marked by mild-life onset and progressive changes in behavior, social cognition, and language. Loss-of-function progranulin gene (GRN) mutations are the major cause of FTLD with TDP-43 protein inclusions (FTLD-TDP). Link: ./index.php?lvl=notice_display&id=26819
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 386-403[artículo] Increasing progranulin levels and blockade of the ERK1/2 pathway : Upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia [texto impreso] / Carolina Alquezar, Autor ; Noemí Esteras, Autor ; Ana De La Encarnación, Autor . - 2021 . - pp. 386-403.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 386-403
Palabras clave: FTLD-TDP, Linfocitos, Proliferación celular, Progranulina, ERK1 / 2, CDK6 Resumen: Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder marked by mild-life onset and progressive changes in behavior, social cognition, and language. Loss-of-function progranulin gene (GRN) mutations are the major cause of FTLD with TDP-43 protein inclusions (FTLD-TDP). Link: ./index.php?lvl=notice_display&id=26819 Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression / Thea Pinholt Lillethorup en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression Tipo de documento: texto impreso Autores: Thea Pinholt Lillethorup, Autor ; Peter Iversen, Autor ; Jesper Fontain, Autor Fecha de publicación: 2021 Artículo en la página: pp. 404-412 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ratas, Flinders, Adrenoceptores α 2, Terapia electroconvulsiva, Autorradiografia Resumen: Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested the hypothesis that the beneficial effect of ECT could in part be the result of increased noradrenergic neurotransmission leading to a decrease in α2-adrenoceptor binding. Link: ./index.php?lvl=notice_display&id=26820
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 404-412[artículo] Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression [texto impreso] / Thea Pinholt Lillethorup, Autor ; Peter Iversen, Autor ; Jesper Fontain, Autor . - 2021 . - pp. 404-412.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 404-412
Palabras clave: Ratas, Flinders, Adrenoceptores α 2, Terapia electroconvulsiva, Autorradiografia Resumen: Despite years of drug development, electroconvulsive therapy (ECT) remains the most effective treatment for severe depression. The exact therapeutic mechanism of action of ECT is still unresolved and therefore we tested the hypothesis that the beneficial effect of ECT could in part be the result of increased noradrenergic neurotransmission leading to a decrease in α2-adrenoceptor binding. Link: ./index.php?lvl=notice_display&id=26820 The atypical antipsychotic clozapine selectively inhibits interleukin 8 (IL-8)-induced neutrophil chemotaxis / Marta Capannolo en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : The atypical antipsychotic clozapine selectively inhibits interleukin 8 (IL-8)-induced neutrophil chemotaxis Tipo de documento: texto impreso Autores: Marta Capannolo, Autor ; Irene Fasciani, Autor ; Stefania Romeo, Autor Fecha de publicación: 2021 Artículo en la página: pp. 413-424 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Clozapina, Quimiotaxis de neutrófilos, Agranulocitosis, Proteínas de resistencia a múltiples fármacos, Leucotrieno B4 Resumen: Clozapine is the most effective antipsychotic to date, but its benefits are counterbalanced by the risk of severe hematological effects. In this study, we analyzed whether clozapine inhibits polymorphonuclear (PMN) leukocyte chemotaxis. Link: ./index.php?lvl=notice_display&id=26821
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 413-424[artículo] The atypical antipsychotic clozapine selectively inhibits interleukin 8 (IL-8)-induced neutrophil chemotaxis [texto impreso] / Marta Capannolo, Autor ; Irene Fasciani, Autor ; Stefania Romeo, Autor . - 2021 . - pp. 413-424.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 413-424
Palabras clave: Clozapina, Quimiotaxis de neutrófilos, Agranulocitosis, Proteínas de resistencia a múltiples fármacos, Leucotrieno B4 Resumen: Clozapine is the most effective antipsychotic to date, but its benefits are counterbalanced by the risk of severe hematological effects. In this study, we analyzed whether clozapine inhibits polymorphonuclear (PMN) leukocyte chemotaxis. Link: ./index.php?lvl=notice_display&id=26821 Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner / Odeya Damri en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner Tipo de documento: texto impreso Autores: Odeya Damri, Autor ; Yeala Sade, Autor ; Lilach Toker, Autor Fecha de publicación: 2021 Artículo en la página: pp. 425-434 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Litio, Inositol monofosfatasa1, Ratones knockout, Expresion genica, Niveles de citocinas Resumen: We have previously shown that homozygote knockout (KO) of inositol-monophosphatase1 (IMPA1) results in lithium (Li)-like behavior. We now aimed to find out whether Li-treated mice and IMPA1 KO mice exhibit neurochemical similarity at the gene- and protein-expression level. Link: ./index.php?lvl=notice_display&id=26822
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 425-434[artículo] Molecular effects of lithium are partially mimicked by inositol-monophosphatase (IMPA)1 knockout mice in a brain region-dependent manner [texto impreso] / Odeya Damri, Autor ; Yeala Sade, Autor ; Lilach Toker, Autor . - 2021 . - pp. 425-434.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 425-434
Palabras clave: Litio, Inositol monofosfatasa1, Ratones knockout, Expresion genica, Niveles de citocinas Resumen: We have previously shown that homozygote knockout (KO) of inositol-monophosphatase1 (IMPA1) results in lithium (Li)-like behavior. We now aimed to find out whether Li-treated mice and IMPA1 KO mice exhibit neurochemical similarity at the gene- and protein-expression level. Link: ./index.php?lvl=notice_display&id=26822 The chemical interaction between adrenochrome, three different classes of antipsychotic drugs and metabolites of the kynurenine pathway / Christine L. Miller en European Neuropsychopharmacology, Año 2015 - Vol. 25 - No.3 (Marzo)
[artículo]
Título : The chemical interaction between adrenochrome, three different classes of antipsychotic drugs and metabolites of the kynurenine pathway Tipo de documento: texto impreso Autores: Christine L. Miller, Autor Fecha de publicación: 2021 Artículo en la página: pp. 435-440 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Eficacia antipsicótica, Reacciones químicas, Neuromelanina, Quinonas, Catarata, Psicosis Resumen: Two kynurenine metabolites, 3-hydroxykynurenine and 3-hydroxyanthranilic acid, are known to inhibit melanin polymer formation in in vitro reactions catalyzed by tyrosinase. Link: ./index.php?lvl=notice_display&id=26823
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 435-440[artículo] The chemical interaction between adrenochrome, three different classes of antipsychotic drugs and metabolites of the kynurenine pathway [texto impreso] / Christine L. Miller, Autor . - 2021 . - pp. 435-440.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2015 - Vol. 25 - No.3 (Marzo) . - pp. 435-440
Palabras clave: Eficacia antipsicótica, Reacciones químicas, Neuromelanina, Quinonas, Catarata, Psicosis Resumen: Two kynurenine metabolites, 3-hydroxykynurenine and 3-hydroxyanthranilic acid, are known to inhibit melanin polymer formation in in vitro reactions catalyzed by tyrosinase. Link: ./index.php?lvl=notice_display&id=26823