Artículos

Historical and cultural aspects of man's relationship with addictive drugs / Marc-Antoine Crocq en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 355–361 Título : Historical and cultural aspects of man's relationship with addictive drugs Tipo de documento: texto impreso Autores: Marc-Antoine Crocq, Autor Fecha de publicación: 2022 Artículo en la página: pp. 355–361 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Adiccion, Dependencia, Drogas, Historia, Cultura Resumen: Our taste for addictive psychoactive substances is attested to in the earliest human records. Historically, psychoactive substances have been used by (i) priests in religious ceremonies (eg, amanita muscaria); (ii) healers for medicinal purposes (eg, opium); or (iii) the general population in a socially approved way (eg, alcohol, nicotine, and caffeine). Link: ./index.php?lvl=notice_display&id=28684 [artículo] Historical and cultural aspects of man's relationship with addictive drugs [texto impreso] / Marc-Antoine Crocq, Autor . - 2022 . - pp. 355–361. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 355–361 Palabras clave: Adiccion, Dependencia, Drogas, Historia, Cultura Resumen: Our taste for addictive psychoactive substances is attested to in the earliest human records. Historically, psychoactive substances have been used by (i) priests in religious ceremonies (eg, amanita muscaria); (ii) healers for medicinal purposes (eg, opium); or (iii) the general population in a socially approved way (eg, alcohol, nicotine, and caffeine). Link: ./index.php?lvl=notice_display&id=28684

Opioids, dopamine, stress, and the addictions / Mary Jeanne Kreek en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 363–378 Título : Opioids, dopamine, stress, and the addictions Tipo de documento: texto impreso Autores: Mary Jeanne Kreek, Autor Fecha de publicación: 2022 Artículo en la página: pp. 363–378 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Opioides, Dopamina, Estrés, Adicción a opiáceos, Adicción a la cocaína, Polimorfismos Resumen: The articulated goals of Dialogues in Clinical Neuroscience are to serve as “an interface between clinical neuropsychiatry and the neurosciences by providing state-of-the-art information and original insights into relevant clinical, biological, and therapeutic aspects.” My laboratory, the Laboratory of the Biology of Addictive Diseases at The Rockefeller University, has for years been focused on “bi-directional translational research,”... Link: ./index.php?lvl=notice_display&id=28685 [artículo] Opioids, dopamine, stress, and the addictions [texto impreso] / Mary Jeanne Kreek, Autor . - 2022 . - pp. 363–378. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 363–378 Palabras clave: Opioides, Dopamina, Estrés, Adicción a opiáceos, Adicción a la cocaína, Polimorfismos Resumen: The articulated goals of Dialogues in Clinical Neuroscience are to serve as “an interface between clinical neuropsychiatry and the neurosciences by providing state-of-the-art information and original insights into relevant clinical, biological, and therapeutic aspects.” My laboratory, the Laboratory of the Biology of Addictive Diseases at The Rockefeller University, has for years been focused on “bi-directional translational research,”... Link: ./index.php?lvl=notice_display&id=28685

Neural basis of reward and craving - a homeostatic point of view / Martin P. Paulus en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 379–387 Título : Neural basis of reward and craving - a homeostatic point of view Tipo de documento: texto impreso Autores: Martin P. Paulus, Autor Fecha de publicación: 2022 Artículo en la página: pp. 379–387 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Recompensa, Placer, Impulso, Deseo, Interocepción, Insula Resumen: Here, it is argued that the interoceptive system, which provides information about the subjects internal state and is integrated in the insular cortex, and not the subcortical ventral striatum, is the critical neural substrate for reward-related processes. Understanding the internal state of the individual, which is processed via this system, makes it possible to develop new interventions that are aimed at treating reward-dysfunction disorders, ie, substance and alcohol dependence. Link: ./index.php?lvl=notice_display&id=28686 [artículo] Neural basis of reward and craving - a homeostatic point of view [texto impreso] / Martin P. Paulus, Autor . - 2022 . - pp. 379–387. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 379–387 Palabras clave: Recompensa, Placer, Impulso, Deseo, Interocepción, Insula Resumen: Here, it is argued that the interoceptive system, which provides information about the subjects internal state and is integrated in the insular cortex, and not the subcortical ventral striatum, is the critical neural substrate for reward-related processes. Understanding the internal state of the individual, which is processed via this system, makes it possible to develop new interventions that are aimed at treating reward-dysfunction disorders, ie, substance and alcohol dependence. Link: ./index.php?lvl=notice_display&id=28686

Cocaine and amphetamine-like psychostimulants / Peter Kalivas en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 389–397 Título : Cocaine and amphetamine-like psychostimulants : neurocircuitry and glutamate neuroplasticity Tipo de documento: texto impreso Autores: Peter Kalivas, Autor Fecha de publicación: 2022 Artículo en la página: pp. 389–397 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Cocaína, Glutamato, Anfetamina, Accumbens, Corteza prefrontal, Dopamina Resumen: Although the pharmacology of amphetamine-like psychostimulants at dopamine transporters is well understood, addiction to this class of drugs has proven difficult to deal with. The reason for this disconnection is that while the molecular mechanism of amphetamine action is critical to reinforce drug use, it is only the first step in a sequence of widespread neuroplastic events in brain circuitry. Link: ./index.php?lvl=notice_display&id=28687 [artículo] Cocaine and amphetamine-like psychostimulants : neurocircuitry and glutamate neuroplasticity [texto impreso] / Peter Kalivas, Autor . - 2022 . - pp. 389–397. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 389–397 Palabras clave: Cocaína, Glutamato, Anfetamina, Accumbens, Corteza prefrontal, Dopamina Resumen: Although the pharmacology of amphetamine-like psychostimulants at dopamine transporters is well understood, addiction to this class of drugs has proven difficult to deal with. The reason for this disconnection is that while the molecular mechanism of amphetamine action is critical to reinforce drug use, it is only the first step in a sequence of widespread neuroplastic events in brain circuitry. Link: ./index.php?lvl=notice_display&id=28687

Outpatient Long term Intensive Therapy for Alcoholics (OLITA) / Henning Krampe en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 399–412 Título : Outpatient Long term Intensive Therapy for Alcoholics (OLITA) : a successful biopsychosocial approach to the treatment of alcoholism Tipo de documento: texto impreso Autores: Henning Krampe, Autor ; Sabina Stawicki, Autor ; Margret R. Hoehe, Autor Fecha de publicación: 2022 Artículo en la página: pp. 399–412 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alcohol, Terapia del alcoholismo, Adicción, Enfermedad psiquiátrica crónica, Tratamiento integrado a largo plazo, Alianza terapéutica, Proceso y resultado de la terapia Resumen: Alcohol dependence is a frequent, chronic, relapsing, and incurable disease with enormous societal costs. Thus, alcoholism therapy and research into its outcome are of major importance for public health. The present article will: (i) give a brief overview of the epidemiology, pathogenesis, and treatment outcomes of alcohol dependence; (ii) introduce the basic principles of outpatient long-term therapy of alcohol-dependent patients;... Link: ./index.php?lvl=notice_display&id=28688 [artículo] Outpatient Long term Intensive Therapy for Alcoholics (OLITA) : a successful biopsychosocial approach to the treatment of alcoholism [texto impreso] / Henning Krampe, Autor ; Sabina Stawicki, Autor ; Margret R. Hoehe, Autor . - 2022 . - pp. 399–412. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 399–412 Palabras clave: Alcohol, Terapia del alcoholismo, Adicción, Enfermedad psiquiátrica crónica, Tratamiento integrado a largo plazo, Alianza terapéutica, Proceso y resultado de la terapia Resumen: Alcohol dependence is a frequent, chronic, relapsing, and incurable disease with enormous societal costs. Thus, alcoholism therapy and research into its outcome are of major importance for public health. The present article will: (i) give a brief overview of the epidemiology, pathogenesis, and treatment outcomes of alcohol dependence; (ii) introduce the basic principles of outpatient long-term therapy of alcohol-dependent patients;... Link: ./index.php?lvl=notice_display&id=28688

Cannabinoids in health and disease / Natalya M. Kogan en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 413–430 Título : Cannabinoids in health and disease Tipo de documento: texto impreso Autores: Natalya M. Kogan, Autor ; Raphael M. Mechoulam, Autor Fecha de publicación: 2022 Artículo en la página: pp. 413–430 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Cannabinoides, Terapéutica, Medicinal, Adicción Resumen: Cannabis sativa L. preparations have been used in medicine for millenia. However, concern over the dangers of abuse led to the banning of the medicinal use of marijuana in most countries in the 1930s. Only recently, marijuana and individual natural and synthetic cannabinoid receptor agonists and antagonists, as well as chemically related compounds, whose mechanism of action is still obscure, have come back to being considered of therapeutic value. Link: ./index.php?lvl=notice_display&id=28689 [artículo] Cannabinoids in health and disease [texto impreso] / Natalya M. Kogan, Autor ; Raphael M. Mechoulam, Autor . - 2022 . - pp. 413–430. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 413–430 Palabras clave: Cannabinoides, Terapéutica, Medicinal, Adicción Resumen: Cannabis sativa L. preparations have been used in medicine for millenia. However, concern over the dangers of abuse led to the banning of the medicinal use of marijuana in most countries in the 1930s. Only recently, marijuana and individual natural and synthetic cannabinoid receptor agonists and antagonists, as well as chemically related compounds, whose mechanism of action is still obscure, have come back to being considered of therapeutic value. Link: ./index.php?lvl=notice_display&id=28689

Therapeutic options and challenges for substances of abuse / Tracie J. Gardner en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 431–445 Título : Therapeutic options and challenges for substances of abuse Tipo de documento: texto impreso Autores: Tracie J. Gardner, Autor ; Thomas R. Kosten, Autor Fecha de publicación: 2022 Artículo en la página: pp. 431–445 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos adictivos, Abuso de sustancias Resumen: Addiction to substances continues to be a significant public health concern in the United States. The following review of current pharmacological treatments discusses a range of substances: nicotine, alcohol, cocaine, and opioids. The goal is to provide an overview of currently available and new pharmacological treatments for substance use disorders, while also addressing the pharmacothera-peutic challenges remaining. Link: ./index.php?lvl=notice_display&id=28690 [artículo] Therapeutic options and challenges for substances of abuse [texto impreso] / Tracie J. Gardner, Autor ; Thomas R. Kosten, Autor . - 2022 . - pp. 431–445. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 431–445 Palabras clave: Trastornos adictivos, Abuso de sustancias Resumen: Addiction to substances continues to be a significant public health concern in the United States. The following review of current pharmacological treatments discusses a range of substances: nicotine, alcohol, cocaine, and opioids. The goal is to provide an overview of currently available and new pharmacological treatments for substance use disorders, while also addressing the pharmacothera-peutic challenges remaining. Link: ./index.php?lvl=notice_display&id=28690

Pharmacogenetic aspects of addictive behaviors / Nadia S. Hejazi en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 447–454 Título : Pharmacogenetic aspects of addictive behaviors Tipo de documento: texto impreso Autores: Nadia S. Hejazi, Autor Fecha de publicación: 2022 Artículo en la página: pp. 447–454 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Adicción, Heredabilidad, Interacción gen-ambiente, Comorbilidad Resumen: Addictions are illnesses of complex causation, including inheritance and a role for gene/environment interactions. Functional alleles influencing pharmacodynamic (tissue response) and pharmacokinetic (absorption, distribution, and metabolism) play a role, but these interact with diverse environmental factors including early Ife stress, underage drug exposure, availability of addictive agents, and response to clinical interventions including pharmacotherapies. Link: ./index.php?lvl=notice_display&id=28691 [artículo] Pharmacogenetic aspects of addictive behaviors [texto impreso] / Nadia S. Hejazi, Autor . - 2022 . - pp. 447–454. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 447–454 Palabras clave: Adicción, Heredabilidad, Interacción gen-ambiente, Comorbilidad Resumen: Addictions are illnesses of complex causation, including inheritance and a role for gene/environment interactions. Functional alleles influencing pharmacodynamic (tissue response) and pharmacokinetic (absorption, distribution, and metabolism) play a role, but these interact with diverse environmental factors including early Ife stress, underage drug exposure, availability of addictive agents, and response to clinical interventions including pharmacotherapies. Link: ./index.php?lvl=notice_display&id=28691

Pharmacologic treatments for opioid dependence / Herbert D. Kleber en Dialogues in Clinical Neuroscience, Año 2007 Vol.9 - No.4 (Diciembre)

Público ISBD [artículo]  inDialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 455–470 Título : Pharmacologic treatments for opioid dependence : detoxification and maintenance options Tipo de documento: texto impreso Autores: Herbert D. Kleber, Autor Fecha de publicación: 2022 Artículo en la página: pp. 455–470 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Dependencia de opiáceos, Desintoxicación, Mantenimiento, Metadona, Buprenorfina, Clonidina, Naltrexona, Tratamiento farmacológico Resumen: While opioid dependence has more treatment agents available than other abused drugs, none are curative. They can, however, markedly diminish withdrawal symptoms and craving, and block opioid effects due to lapses. Link: ./index.php?lvl=notice_display&id=28692 [artículo] Pharmacologic treatments for opioid dependence : detoxification and maintenance options [texto impreso] / Herbert D. Kleber, Autor . - 2022 . - pp. 455–470. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Dialogues in Clinical Neuroscience > Año 2007 Vol.9 - No.4 (Diciembre) . - pp. 455–470 Palabras clave: Dependencia de opiáceos, Desintoxicación, Mantenimiento, Metadona, Buprenorfina, Clonidina, Naltrexona, Tratamiento farmacológico Resumen: While opioid dependence has more treatment agents available than other abused drugs, none are curative. They can, however, markedly diminish withdrawal symptoms and craving, and block opioid effects due to lapses. Link: ./index.php?lvl=notice_display&id=28692