Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression / Vanina Popova en The American Journal of Psychiatry, Año 2019 - Vol. 176 - No. 6 (Junio)

Público ISBD [artículo]  inThe American Journal of Psychiatry > Año 2019 - Vol. 176 - No. 6 (Junio) . - pp. 428-438 Título : Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression : A randomized double-blind active-controlled study Tipo de documento: texto impreso Autores: Vanina Popova, Autor ; Ella J. Daly, Autor ; Madhukar H. Trivedi, Autor Fecha de publicación: 2019 Artículo en la página: pp. 428-438 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Esketamina, SKetamine, Ketamina, Depresión resistente al tratamiento, Trastorno depresivo mayor Resumen: About one-third of patients with depression fail to achieve remission despite treatment with multiple antidepressants. This study compared the efficacy and safety of switching patients with treatment-resistant depression from an ineffective antidepressant to flexibly dosed esketamine nasal spray plus a newly initiated antidepressant or to a newly initiated antidepressant (active comparator) plus placebo nasal spray. Link: ./index.php?lvl=notice_display&id=20716 [artículo] Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression : A randomized double-blind active-controlled study [texto impreso] / Vanina Popova, Autor ; Ella J. Daly, Autor ; Madhukar H. Trivedi, Autor . - 2019 . - pp. 428-438. Idioma : Inglés (eng) Idioma original : Inglés (eng) in The American Journal of Psychiatry > Año 2019 - Vol. 176 - No. 6 (Junio) . - pp. 428-438 Palabras clave: Esketamina, SKetamine, Ketamina, Depresión resistente al tratamiento, Trastorno depresivo mayor Resumen: About one-third of patients with depression fail to achieve remission despite treatment with multiple antidepressants. This study compared the efficacy and safety of switching patients with treatment-resistant depression from an ineffective antidepressant to flexibly dosed esketamine nasal spray plus a newly initiated antidepressant or to a newly initiated antidepressant (active comparator) plus placebo nasal spray. Link: ./index.php?lvl=notice_display&id=20716

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