Biblioteca Humberto Rosselli Quijano
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Año 2000 - Vol. 20 - No. 6 - Diciembre - Journal of Clínical Psychopharmacology [texto impreso] / Richard I. Shader, Autor ; David J. Greenblatt, Autor . - 2023 . - pp. 593-736 : Cuadros, gráficas ; 28 cm. ISSN : 0271-0749 Idioma : Inglés (eng) Idioma original : Inglés (eng) |  |
Ejemplares (1)
| Código de barras | Signatura | Tipo de medio | Ubicación | Sección | Estado |
|---|---|---|---|---|---|
| 100275 | Journal of Clinical Psychopharmacology | Publicaciones seriadas | Biblioteca Instituto Colombiano del Sistema Nervioso | Hemeroteca | Disponible |
Artículos
Añadir el resultado a su cestaComparative abuse liability of intravenously administered remifentanil and fentanyl / Godofredo J. Baylon en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 6 (Diciembre)
Título : Comparative abuse liability of intravenously administered remifentanil and fentanyl Tipo de documento: texto impreso Autores: Godofredo J. Baylon, Autor ; Howard L. Kaplan, Autor ; Gail Somer, Autor Fecha de publicación: 2023 Artículo en la página: pp. 597-606 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Opioides, Fentanilo, Piperidinas, Efectos de pupila, Trastornos relacionados con sustancias. Resumen: Remifentanil is a short-acting, esterase-metabolized opioid analgesic. This study compared the abuse liability of remifentanil with that of fentanyl and placebo in a randomized, double-blind, crossover study. Twelve recreational users of opioids received increasing doses of remifentanil (0.6, 1.2, 1.8, 2.4, and 3.0 μg/kg), fentanyl (0.4, 0.8, 1.3, 2.0, 3.0, and 4.5 μg/kg) and placebo via an intravenous infusion pump. Link: ./index.php?lvl=notice_display&id=31149
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 597-606[artículo] Comparative abuse liability of intravenously administered remifentanil and fentanyl [texto impreso] / Godofredo J. Baylon, Autor ; Howard L. Kaplan, Autor ; Gail Somer, Autor . - 2023 . - pp. 597-606.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 597-606
Palabras clave: Afecto, Opioides, Fentanilo, Piperidinas, Efectos de pupila, Trastornos relacionados con sustancias. Resumen: Remifentanil is a short-acting, esterase-metabolized opioid analgesic. This study compared the abuse liability of remifentanil with that of fentanyl and placebo in a randomized, double-blind, crossover study. Twelve recreational users of opioids received increasing doses of remifentanil (0.6, 1.2, 1.8, 2.4, and 3.0 μg/kg), fentanyl (0.4, 0.8, 1.3, 2.0, 3.0, and 4.5 μg/kg) and placebo via an intravenous infusion pump. Link: ./index.php?lvl=notice_display&id=31149
Título : A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders Tipo de documento: texto impreso Autores: Mark A. Frye, Autor ; Terence A. Ketter, Autor ; Timothy A. Kimbrell, Autor Fecha de publicación: 2023 Artículo en la página: pp. 607-614 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antimaníacos, Trastornos del estado de ánimo, Trastornos del estado de ánimo, Triazinas. Resumen: There is a pressing need for additional treatment options for refractory mood disorders. This controlled comparative study evaluated the efficacy of lamotrigine (LTG) and gabapentin (GBP) monotherapy versus placebo (PLC). Thirty-one patients with refractory bipolar and unipolar mood disorders participated in a double-blind, randomized, crossover series of three 6-week monotherapy evaluations including LTG, GBP, and PLC. Link: ./index.php?lvl=notice_display&id=31150
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 607-614[artículo] A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders [texto impreso] / Mark A. Frye, Autor ; Terence A. Ketter, Autor ; Timothy A. Kimbrell, Autor . - 2023 . - pp. 607-614.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 607-614
Palabras clave: Antimaníacos, Trastornos del estado de ánimo, Trastornos del estado de ánimo, Triazinas. Resumen: There is a pressing need for additional treatment options for refractory mood disorders. This controlled comparative study evaluated the efficacy of lamotrigine (LTG) and gabapentin (GBP) monotherapy versus placebo (PLC). Thirty-one patients with refractory bipolar and unipolar mood disorders participated in a double-blind, randomized, crossover series of three 6-week monotherapy evaluations including LTG, GBP, and PLC. Link: ./index.php?lvl=notice_display&id=31150
Título : Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder Tipo de documento: texto impreso Autores: Daniel R. McLeod, Autor ; Rudolf Hoehn Saric, Autor ; Stephen W. Porges, Autor Fecha de publicación: 2023 Artículo en la página: pp. 615-621 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Inhibidores de la captación adrenérgica, Trastornos de ansiedad, Arritmias, Presión arterial, Desipramina, Frecuencia cardíaca, Imipramina. Resumen: Imipramine has been shown to reduce anxiety in patients with generalized anxiety disorder (GAD). However, some properties of imipramine may diminish or counteract its anxiolytic effects. The authors previously found that the greater the reduction in cardiac vagal control after 6 weeks of imipramine treatment, the smaller the improvement in anxiety-related symptoms. Link: ./index.php?lvl=notice_display&id=31151
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 615-621[artículo] Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder [texto impreso] / Daniel R. McLeod, Autor ; Rudolf Hoehn Saric, Autor ; Stephen W. Porges, Autor . - 2023 . - pp. 615-621.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 615-621
Palabras clave: Inhibidores de la captación adrenérgica, Trastornos de ansiedad, Arritmias, Presión arterial, Desipramina, Frecuencia cardíaca, Imipramina. Resumen: Imipramine has been shown to reduce anxiety in patients with generalized anxiety disorder (GAD). However, some properties of imipramine may diminish or counteract its anxiolytic effects. The authors previously found that the greater the reduction in cardiac vagal control after 6 weeks of imipramine treatment, the smaller the improvement in anxiety-related symptoms. Link: ./index.php?lvl=notice_display&id=31151
Título : Do antidepressants selectively suppress spontaneous (unexpected) panic attacks? A replication Tipo de documento: texto impreso Autores: Eberhard H. Uhlenhuth, Autor ; William Matuzas, Autor ; Teddy D. Warner, Autor Fecha de publicación: 2023 Artículo en la página: pp. 622-627 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agorafobia, Relación Dosis-Respuesta, Fluoxetina, Trastorno de pánico. Resumen: The purpose of this study was to test the following interrelated hypotheses in a larger sample by attempting to replicate supportive results from a small therapeutic study: (1) the pathogenesis of panic disorder includes at least two identifiable components: a biological component represented by spontaneous (unexpected) panic attacks, and a cognitive component represented by situational attacks and especially by phobias... Link: ./index.php?lvl=notice_display&id=31152
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 622-627[artículo] Do antidepressants selectively suppress spontaneous (unexpected) panic attacks? A replication [texto impreso] / Eberhard H. Uhlenhuth, Autor ; William Matuzas, Autor ; Teddy D. Warner, Autor . - 2023 . - pp. 622-627.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 622-627
Palabras clave: Agorafobia, Relación Dosis-Respuesta, Fluoxetina, Trastorno de pánico. Resumen: The purpose of this study was to test the following interrelated hypotheses in a larger sample by attempting to replicate supportive results from a small therapeutic study: (1) the pathogenesis of panic disorder includes at least two identifiable components: a biological component represented by spontaneous (unexpected) panic attacks, and a cognitive component represented by situational attacks and especially by phobias... Link: ./index.php?lvl=notice_display&id=31152
Título : A comparative pharmacokinetic and dynamic evaluation of alprazolam sustained-release, bromazepam, and lorazepam Tipo de documento: texto impreso Autores: Usoa E. Busto, Autor ; Howard L. Kaplan, Autor ; C. Eugene Wright, Autor Fecha de publicación: 2023 Artículo en la página: pp. 628-635 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Alprazolam, Ansiolíticos, Bromazepam, Lorazepam, Rendimiento psicomotor. Resumen: Sustained-release (SR) alprazolam may facilitate compliance with oral benzodiazepine treatment of panic disorders that currently requires doses administered three or four times daily. To compare the pharmacokinetic, psychomotor performance, and subjective effects of alprazolam SR (1.5 mg), bromazepam (3 mg taken three times daily), and lorazepam (1 mg taken three times daily), 13 male volunteers (aged 20-45 years) randomly received on four separate occasions one of these medications or placebo. Link: ./index.php?lvl=notice_display&id=31153
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 628-635[artículo] A comparative pharmacokinetic and dynamic evaluation of alprazolam sustained-release, bromazepam, and lorazepam [texto impreso] / Usoa E. Busto, Autor ; Howard L. Kaplan, Autor ; C. Eugene Wright, Autor . - 2023 . - pp. 628-635.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 628-635
Palabras clave: Afecto, Alprazolam, Ansiolíticos, Bromazepam, Lorazepam, Rendimiento psicomotor. Resumen: Sustained-release (SR) alprazolam may facilitate compliance with oral benzodiazepine treatment of panic disorders that currently requires doses administered three or four times daily. To compare the pharmacokinetic, psychomotor performance, and subjective effects of alprazolam SR (1.5 mg), bromazepam (3 mg taken three times daily), and lorazepam (1 mg taken three times daily), 13 male volunteers (aged 20-45 years) randomly received on four separate occasions one of these medications or placebo. Link: ./index.php?lvl=notice_display&id=31153
Título : Prevention of relapse in generalized social phobia: results of a 24-week study in responders to 20 weeks of sertraline treatment Tipo de documento: texto impreso Autores: John R. Walker, Autor ; Michael Van Ameringen, Autor ; Richard Swinson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 636-644 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos fóbicos, Inhibidores selectivos de la recaptación de serotonina, Sertralina. Resumen: The aim of this study was to evaluate the efficacy, tolerability, and effects on quality of life of sertraline, a selective serotonin reuptake inhibitor, in the prevention of relapse of generalized social phobia. Fifty adult outpatients with generalized social phobia who were rated much or very much improved on the Clinical Global Impression Scale of Improvement (CGI-I) after 20 weeks of sertraline treatment (50-200 mg/day) were randomly assigned in a one-to-one ratio to either continue double-blind treatment with sertraline or immediately switch to placebo for another 24 weeks. Link: ./index.php?lvl=notice_display&id=31154
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 636-644[artículo] Prevention of relapse in generalized social phobia: results of a 24-week study in responders to 20 weeks of sertraline treatment [texto impreso] / John R. Walker, Autor ; Michael Van Ameringen, Autor ; Richard Swinson, Autor . - 2023 . - pp. 636-644.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 636-644
Palabras clave: Trastornos fóbicos, Inhibidores selectivos de la recaptación de serotonina, Sertralina. Resumen: The aim of this study was to evaluate the efficacy, tolerability, and effects on quality of life of sertraline, a selective serotonin reuptake inhibitor, in the prevention of relapse of generalized social phobia. Fifty adult outpatients with generalized social phobia who were rated much or very much improved on the Clinical Global Impression Scale of Improvement (CGI-I) after 20 weeks of sertraline treatment (50-200 mg/day) were randomly assigned in a one-to-one ratio to either continue double-blind treatment with sertraline or immediately switch to placebo for another 24 weeks. Link: ./index.php?lvl=notice_display&id=31154
Título : Sertraline versus paroxetine in major depression: clinical outcome after six months of continuous therapy Tipo de documento: texto impreso Autores: Anna Åberg Wistedt, Autor ; Hans Ågren, Autor ; Lisa Ekselius, Autor Fecha de publicación: 2023 Artículo en la página: pp. 645-652 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno depresivo mayor, Paroxetina, Trastornos de personalidad, Calidad de Vida - psicología, Sertralina. Resumen: Relatively little research is available comparing the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) during continuation therapy. This investigation reports the differential effect of 6 months of treatment with sertraline versus paroxetine for symptoms of depression, quality of life, and personality outcomes. Link: ./index.php?lvl=notice_display&id=31155
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 645-652[artículo] Sertraline versus paroxetine in major depression: clinical outcome after six months of continuous therapy [texto impreso] / Anna Åberg Wistedt, Autor ; Hans Ågren, Autor ; Lisa Ekselius, Autor . - 2023 . - pp. 645-652.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 645-652
Palabras clave: Trastorno depresivo mayor, Paroxetina, Trastornos de personalidad, Calidad de Vida - psicología, Sertralina. Resumen: Relatively little research is available comparing the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) during continuation therapy. This investigation reports the differential effect of 6 months of treatment with sertraline versus paroxetine for symptoms of depression, quality of life, and personality outcomes. Link: ./index.php?lvl=notice_display&id=31155
Título : Hematologic reference ranges in a population of patients with schizophrenia Tipo de documento: texto impreso Autores: Simon N. Voss, Autor ; Todd Sanger, Autor ; Charles M. Beasley, Autor Fecha de publicación: 2023 Artículo en la página: pp. 653-657 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Negros afroamericanos, Pruebas - hematológia, Leucocitos, Olanzapina, Pirenzepina, Esquizofrenia. Resumen: The potential hematotoxic effects of antipsychotic drugs are well known and may limit the use of some effective therapies. Although some previous studies have suggested that patients with schizophrenia may have altered "normal" values, only limited data were available. It is now believed that biological values do not usually follow a normal distribution; therefore, reference ranges are frequently used when interpreting laboratory tests in clinical practice and in research. Link: ./index.php?lvl=notice_display&id=31156
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 653-657[artículo] Hematologic reference ranges in a population of patients with schizophrenia [texto impreso] / Simon N. Voss, Autor ; Todd Sanger, Autor ; Charles M. Beasley, Autor . - 2023 . - pp. 653-657.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 653-657
Palabras clave: Antipsicóticos, Negros afroamericanos, Pruebas - hematológia, Leucocitos, Olanzapina, Pirenzepina, Esquizofrenia. Resumen: The potential hematotoxic effects of antipsychotic drugs are well known and may limit the use of some effective therapies. Although some previous studies have suggested that patients with schizophrenia may have altered "normal" values, only limited data were available. It is now believed that biological values do not usually follow a normal distribution; therefore, reference ranges are frequently used when interpreting laboratory tests in clinical practice and in research. Link: ./index.php?lvl=notice_display&id=31156
Título : Side effects and time course of response in a placebo-controlled trial of fluoxetine for the treatment of geriatric depression Tipo de documento: texto impreso Autores: Deborah L. Ackerman, Autor ; Sander Greenland, Autor ; Alexander Bystritsky, Autor Fecha de publicación: 2023 Artículo en la página: pp. 658-665 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Intervalos de confianza, Depresión, Fluoxetina Resumen: A high rate of improvement among patients who receive placebo in controlled trials of antidepressants can complicate the evaluation of true drug effect. Placebo response may be a reaction to the psychosocial factors of study participation or a function of changes in the natural course of depression. Drug side effects may also influence patients' expectations, and they should be distinguished from the somatic symptoms associated with major depression. Link: ./index.php?lvl=notice_display&id=31157
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 658-665[artículo] Side effects and time course of response in a placebo-controlled trial of fluoxetine for the treatment of geriatric depression [texto impreso] / Deborah L. Ackerman, Autor ; Sander Greenland, Autor ; Alexander Bystritsky, Autor . - 2023 . - pp. 658-665.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 658-665
Palabras clave: Intervalos de confianza, Depresión, Fluoxetina Resumen: A high rate of improvement among patients who receive placebo in controlled trials of antidepressants can complicate the evaluation of true drug effect. Placebo response may be a reaction to the psychosocial factors of study participation or a function of changes in the natural course of depression. Drug side effects may also influence patients' expectations, and they should be distinguished from the somatic symptoms associated with major depression. Link: ./index.php?lvl=notice_display&id=31157
Título : Changes in energy during treatment of depression: an analysis of fluoxetine in double-blind, placebo-controlled trials Tipo de documento: texto impreso Autores: Rajinder A. Judge, Autor ; John M. Plewes, Autor ; Vinod Kumar, Autor Fecha de publicación: 2023 Artículo en la página: pp. 666-672 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Ensayos clínicos controlados, Trastorno depresivo mayor, Fatiga, Fluoxetina. Resumen: More than two thirds of patients with depression present with symptoms of fatigue, low energy, and listlessness. Because daytime sedation may be a concern in such patients, a "nonsedating" antidepressant should be considered. The authors examined the effects of fluoxetine on depression-related disturbances in energy. Link: ./index.php?lvl=notice_display&id=31158
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 666-672[artículo] Changes in energy during treatment of depression: an analysis of fluoxetine in double-blind, placebo-controlled trials [texto impreso] / Rajinder A. Judge, Autor ; John M. Plewes, Autor ; Vinod Kumar, Autor . - 2023 . - pp. 666-672.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 666-672
Palabras clave: Ensayos clínicos controlados, Trastorno depresivo mayor, Fatiga, Fluoxetina. Resumen: More than two thirds of patients with depression present with symptoms of fatigue, low energy, and listlessness. Because daytime sedation may be a concern in such patients, a "nonsedating" antidepressant should be considered. The authors examined the effects of fluoxetine on depression-related disturbances in energy. Link: ./index.php?lvl=notice_display&id=31158
Título : The drug-placebo response curve: a new method for assessing drug effects in clinical trials Tipo de documento: texto impreso Autores: Stephen V. Faraone, Autor ; Joseph Biederman, Autor ; Thomas J. Spencer, Autor Fecha de publicación: 2023 Artículo en la página: pp. 673-679 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno por déficit de atención con hiperactividad, Ensayos clínicos, Desipramina, Relación dosis-respuesta. Resumen: Unlike many other areas of medicine, psychiatric clinical trials have no gold standard laboratory tests with which to measure drug effects. Although reliable and valid psychometric measures are available, the standard analysis of such measures obscures the clinical relevance of drug effects. In this study, the authors sought to address this problem by developing a graphical display called the drug-placebo response curve. Link: ./index.php?lvl=notice_display&id=31159
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 673-679[artículo] The drug-placebo response curve: a new method for assessing drug effects in clinical trials [texto impreso] / Stephen V. Faraone, Autor ; Joseph Biederman, Autor ; Thomas J. Spencer, Autor . - 2023 . - pp. 673-679.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 673-679
Palabras clave: Trastorno por déficit de atención con hiperactividad, Ensayos clínicos, Desipramina, Relación dosis-respuesta. Resumen: Unlike many other areas of medicine, psychiatric clinical trials have no gold standard laboratory tests with which to measure drug effects. Although reliable and valid psychometric measures are available, the standard analysis of such measures obscures the clinical relevance of drug effects. In this study, the authors sought to address this problem by developing a graphical display called the drug-placebo response curve. Link: ./index.php?lvl=notice_display&id=31159
Título : A double-blind, placebo-controlled study on the effects of gotu kola (centella asiatica) on acoustic startle response in healthy subjects Tipo de documento: texto impreso Autores: Jacques Bradwejn, Autor ; Yueping Zhou, Autor ; Diana Koszycki, Autor Fecha de publicación: 2023 Artículo en la página: pp. 680-684 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Ansiolíticos, Presión arterial, Frecuencia cardíaca, Medicina China Tradicional, Extractos de Plantas. Resumen: Investigations of the pharmacologic profile of medicinal plants have revealed that a number of plants with purported anxiolytic activity bind to cholecystokinin (CCK) receptors. This finding is intriguing in view of the proposed involvement of CCK in the pathophysiology of fear and anxiety. This double-blind, placebo-controlled study was undertaken to evaluate the anxiolytic activity of Gotu Kola (Centella asiatica) in healthy subjects. Link: ./index.php?lvl=notice_display&id=31160
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 680-684[artículo] A double-blind, placebo-controlled study on the effects of gotu kola (centella asiatica) on acoustic startle response in healthy subjects [texto impreso] / Jacques Bradwejn, Autor ; Yueping Zhou, Autor ; Diana Koszycki, Autor . - 2023 . - pp. 680-684.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 680-684
Palabras clave: Afecto, Ansiolíticos, Presión arterial, Frecuencia cardíaca, Medicina China Tradicional, Extractos de Plantas. Resumen: Investigations of the pharmacologic profile of medicinal plants have revealed that a number of plants with purported anxiolytic activity bind to cholecystokinin (CCK) receptors. This finding is intriguing in view of the proposed involvement of CCK in the pathophysiology of fear and anxiety. This double-blind, placebo-controlled study was undertaken to evaluate the anxiolytic activity of Gotu Kola (Centella asiatica) in healthy subjects. Link: ./index.php?lvl=notice_display&id=31160
Título : Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in japanese patients Tipo de documento: texto impreso Autores: Eiji Yukawa, Autor ; Tsuyoshi Hokazono, Autor ; Akiko Funakoshi, Autor Fecha de publicación: 2023 Artículo en la página: pp. 685-690 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Haloperidol, Japón, Modelos biológicos, Esquizofrenia. Resumen: The steady-state trough concentrations of haloperidol were studied to clarify the role of the characteristics of Japanese patients in estimating haloperidol dosing regimens by using routine therapeutic drug-monitoring data. Nonlinear mixed-effects modeling (NONMEM) was used to estimate the effect of a variety of developmental and demographic factors on haloperidol clearance values using 270 serum level measurements obtained from 191 patients during their clinical course. Link: ./index.php?lvl=notice_display&id=31161
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 685-690[artículo] Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in japanese patients [texto impreso] / Eiji Yukawa, Autor ; Tsuyoshi Hokazono, Autor ; Akiko Funakoshi, Autor . - 2023 . - pp. 685-690.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 6 (Diciembre) . - pp. 685-690
Palabras clave: Antipsicóticos, Haloperidol, Japón, Modelos biológicos, Esquizofrenia. Resumen: The steady-state trough concentrations of haloperidol were studied to clarify the role of the characteristics of Japanese patients in estimating haloperidol dosing regimens by using routine therapeutic drug-monitoring data. Nonlinear mixed-effects modeling (NONMEM) was used to estimate the effect of a variety of developmental and demographic factors on haloperidol clearance values using 270 serum level measurements obtained from 191 patients during their clinical course. Link: ./index.php?lvl=notice_display&id=31161
