Biblioteca Humberto Rosselli Quijano
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Año 2000 - Vol. 20 - No. 3 - Junio - Journal of Clínical Psychopharmacology [texto impreso] / Richard I. Shader, Editor científico ; David J. Greenblatt, Editor científico . - 2023 . - pp. 291-396 : Cuadros, gráficas ; 28 cm. ISSN : 0271-0749 Idioma : Inglés (eng) Idioma original : Inglés (eng) |  |
Ejemplares (1)
| Código de barras | Signatura | Tipo de medio | Ubicación | Sección | Estado |
|---|---|---|---|---|---|
| 100272 | Journal of Clinical Psychopharmacology | Publicaciones seriadas | Biblioteca Instituto Colombiano del Sistema Nervioso | Hemeroteca | Disponible |
Artículos
Añadir el resultado a su cestaLongitudinal comparative study of risperidone and conventional neuroleptics for treating patients with schizophrenia / Roch Hugo Bouchard en Journal of Clinical Psychopharmacology, Año 2000 - Vol. 20 - No. 3 (Junio)
Título : Longitudinal comparative study of risperidone and conventional neuroleptics for treating patients with schizophrenia Tipo de documento: texto impreso Autores: Roch Hugo Bouchard, Autor ; Chantal Mérette, Autor ; Emmanuelle Pourcher, Autor Fecha de publicación: 2023 Artículo en la página: pp. 295-304 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Enfermedad crónica, Abandono de pacientes, Risperidona, Esquizofrenia. Resumen: This study compared the long-term (12 months) effectiveness of risperidone (RP) with that of conventional neuroleptics (CNs) in a population with chronic schizophrenia who had shown suboptimal response to CNs. A randomized, open, parallel, multicenter design was used. One hundred eighty-four subjects meeting DSM-IV criteria for schizophrenia were randomly assigned to receive either RP or a CN, and 165 of them completed the follow-up. Link: ./index.php?lvl=notice_display&id=31186
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 295-304[artículo] Longitudinal comparative study of risperidone and conventional neuroleptics for treating patients with schizophrenia [texto impreso] / Roch Hugo Bouchard, Autor ; Chantal Mérette, Autor ; Emmanuelle Pourcher, Autor . - 2023 . - pp. 295-304.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 295-304
Palabras clave: Antipsicóticos, Enfermedad crónica, Abandono de pacientes, Risperidona, Esquizofrenia. Resumen: This study compared the long-term (12 months) effectiveness of risperidone (RP) with that of conventional neuroleptics (CNs) in a population with chronic schizophrenia who had shown suboptimal response to CNs. A randomized, open, parallel, multicenter design was used. One hundred eighty-four subjects meeting DSM-IV criteria for schizophrenia were randomly assigned to receive either RP or a CN, and 165 of them completed the follow-up. Link: ./index.php?lvl=notice_display&id=31186
Título : Risperidone for the treatment of cocaine dependence: randomized, double-blind trial Tipo de documento: texto impreso Autores: John Grabowski, Autor ; Howard Rhoades, Autor ; Peter Silverman, Autor Fecha de publicación: 2023 Artículo en la página: pp. 305-310 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Cocaína, Trastornos relacionados con la cocaína, Antagonistas de la dopamina, Abandono de pacientes, Psicoterapia, Risperidona Resumen: A partial blockade of the multiple actions of cocaine is one strategy by which cocaine dependence may be treated. Risperidone, a 5-hydroxytryptamine and dopamine D2 antagonist, is an atypical antipsychotic and was a candidate medication for the treatment of cocaine dependence. One hundred ninety-three cocaine-dependent subjects were enrolled in a 12-week, randomized, double-blind, placebo-controlled trial. Link: ./index.php?lvl=notice_display&id=31187
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 305-310[artículo] Risperidone for the treatment of cocaine dependence: randomized, double-blind trial [texto impreso] / John Grabowski, Autor ; Howard Rhoades, Autor ; Peter Silverman, Autor . - 2023 . - pp. 305-310.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 305-310
Palabras clave: Cocaína, Trastornos relacionados con la cocaína, Antagonistas de la dopamina, Abandono de pacientes, Psicoterapia, Risperidona Resumen: A partial blockade of the multiple actions of cocaine is one strategy by which cocaine dependence may be treated. Risperidone, a 5-hydroxytryptamine and dopamine D2 antagonist, is an atypical antipsychotic and was a candidate medication for the treatment of cocaine dependence. One hundred ninety-three cocaine-dependent subjects were enrolled in a 12-week, randomized, double-blind, placebo-controlled trial. Link: ./index.php?lvl=notice_display&id=31187
Título : Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with tourette syndrome Tipo de documento: texto impreso Autores: David A. Flockhart, Autor ; Milou Daniel Drici, Autor ; Thomas Kerbusch, Autor Fecha de publicación: 2023 Artículo en la página: pp. 317-324 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Claritromicina, Muerte súbita, Electrocardiografía, Microsomas, Pimozida, Síndrome de Tourette. Resumen: The authors report in detail the case of a 27-year-old man who experienced sudden cardiac death 2 days after coprescription of the neuroleptic pimozide and the macrolide antibiotic clarithromycin after the documentation of a prolonged QT interval. To determine the prevalence of this interaction, the authors referred to the Spontaneous Reporting System of the Food and Drug Administration and identified one similar case in which clarithromycin was coprescribed with pimozide and sudden cardiac death occurred shortly thereafter. Link: ./index.php?lvl=notice_display&id=31189
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 317-324[artículo] Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with tourette syndrome [texto impreso] / David A. Flockhart, Autor ; Milou Daniel Drici, Autor ; Thomas Kerbusch, Autor . - 2023 . - pp. 317-324.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 317-324
Palabras clave: Antipsicóticos, Claritromicina, Muerte súbita, Electrocardiografía, Microsomas, Pimozida, Síndrome de Tourette. Resumen: The authors report in detail the case of a 27-year-old man who experienced sudden cardiac death 2 days after coprescription of the neuroleptic pimozide and the macrolide antibiotic clarithromycin after the documentation of a prolonged QT interval. To determine the prevalence of this interaction, the authors referred to the Spontaneous Reporting System of the Food and Drug Administration and identified one similar case in which clarithromycin was coprescribed with pimozide and sudden cardiac death occurred shortly thereafter. Link: ./index.php?lvl=notice_display&id=31189
Título : Sudden death in patients receiving clozapine treatment: a preliminary investigation Tipo de documento: texto impreso Autores: Ilan Modai, Autor ; Shmuel Hirschmann, Autor ; Alla Rava, Autor Fecha de publicación: 2023 Artículo en la página: pp. 325-327 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agentes antipsicóticos, Clozapina, Muerte súbita, Suicidio. Resumen: The risk of sudden death during clozapine treatment is controversial. The authors present a review of sudden deaths that occurred at Sha'ar Menashe Mental Health Center between January 1991 and August 1997. The number of cases of deceased inpatients was retrieved from the hospital's computerized database and divided into three groups: sudden death, suicide, and disease-related death. Link: ./index.php?lvl=notice_display&id=31190
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 325-327[artículo] Sudden death in patients receiving clozapine treatment: a preliminary investigation [texto impreso] / Ilan Modai, Autor ; Shmuel Hirschmann, Autor ; Alla Rava, Autor . - 2023 . - pp. 325-327.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 325-327
Palabras clave: Agentes antipsicóticos, Clozapina, Muerte súbita, Suicidio. Resumen: The risk of sudden death during clozapine treatment is controversial. The authors present a review of sudden deaths that occurred at Sha'ar Menashe Mental Health Center between January 1991 and August 1997. The number of cases of deceased inpatients was retrieved from the hospital's computerized database and divided into three groups: sudden death, suicide, and disease-related death. Link: ./index.php?lvl=notice_display&id=31190
Título : Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance Tipo de documento: texto impreso Autores: Steven M. Troy, Autor ; Irwin Lucki, Autor ; Mary A. Unruh, Autor Fecha de publicación: 2023 Artículo en la página: pp. 328-337 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Afecto, Hipnóticos y Sedantes, Aprendizaje - efectos del medicamento, Memoria, Recuerdo mental, Rendimiento psicomotor, Piridinas, Pirimidinas, Triazolam. Resumen: Twenty-four healthy male and female subjects, who participated in this randomized, double-blind, crossover study, received single nighttime doses of zaleplon 10 mg (therapeutic dose), zaleplon 20 mg, zolpidem 10 mg (therapeutic dose), zolpidem 20 mg, triazolam 0.25 mg (positive control), and placebo. Subjective behavioral ratings and psychomotor tests were completed before and 1.25 and 8.25 hours after administration of the study drug. Link: ./index.php?lvl=notice_display&id=31191
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 328-337[artículo] Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance [texto impreso] / Steven M. Troy, Autor ; Irwin Lucki, Autor ; Mary A. Unruh, Autor . - 2023 . - pp. 328-337.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 328-337
Palabras clave: Afecto, Hipnóticos y Sedantes, Aprendizaje - efectos del medicamento, Memoria, Recuerdo mental, Rendimiento psicomotor, Piridinas, Pirimidinas, Triazolam. Resumen: Twenty-four healthy male and female subjects, who participated in this randomized, double-blind, crossover study, received single nighttime doses of zaleplon 10 mg (therapeutic dose), zaleplon 20 mg, zolpidem 10 mg (therapeutic dose), zolpidem 20 mg, triazolam 0.25 mg (positive control), and placebo. Subjective behavioral ratings and psychomotor tests were completed before and 1.25 and 8.25 hours after administration of the study drug. Link: ./index.php?lvl=notice_display&id=31191
Título : Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam Tipo de documento: texto impreso Autores: Gary B. Kaplan, Autor ; David J. Greenblatt, Autor ; Bruce L. Ehrenberg, Autor Fecha de publicación: 2023 Artículo en la página: pp. 338-346 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alprazolam, Ansiolíticos, Electroencefalografía, Trastorno de pánico. Resumen: The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers. Subjects received orally administered placebo and alprazolam in a randomized, double-blind, single-dose crossover study. Link: ./index.php?lvl=notice_display&id=31192
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 338-346[artículo] Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam [texto impreso] / Gary B. Kaplan, Autor ; David J. Greenblatt, Autor ; Bruce L. Ehrenberg, Autor . - 2023 . - pp. 338-346.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 338-346
Palabras clave: Alprazolam, Ansiolíticos, Electroencefalografía, Trastorno de pánico. Resumen: The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers. Subjects received orally administered placebo and alprazolam in a randomized, double-blind, single-dose crossover study. Link: ./index.php?lvl=notice_display&id=31192
Título : Single dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers Tipo de documento: texto impreso Autores: C. Lindsay DeVane, Autor ; John C. Markowitz, Autor ; Stanley W. Carson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 347-349 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Inhibidores del citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31193
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349[artículo] Single dose pharmacokinetics of methylphenidate in CYP2D6 extensive and poor metabolizers [texto impreso] / C. Lindsay DeVane, Autor ; John C. Markowitz, Autor ; Stanley W. Carson, Autor . - 2023 . - pp. 347-349.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349
Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Inhibidores del citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31193
Título : A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments Tipo de documento: texto impreso Autores: Yvonne M. Greene, Autor ; Pierre N. Tariot, Autor ; Heather Wishart, Autor Fecha de publicación: 2023 Artículo en la página: pp. 350-356 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos cognitivos, Indanos - efectos adversos, Indios, Esclerosis múltiple, Agentes Nootrópicos, Piperidinas. Resumen: Cognitive dysfunction occurs in up to 65% of patients with multiple sclerosis (MS), but there is no effective treatment for the symptoms. The authors conducted a 12-week, open-pilot study to assess the efficacy and tolerability of donepezil HCl administered in patients with MS and cognitive impairment. Seventeen patients at a long-term care facility with Mini-Mental State Examination scores of ≤ 25 received 5 mg of donepezil HCl for a 4-week period, followed by 8 weeks of 10 mg of donepezil HCl. Link: ./index.php?lvl=notice_display&id=31194
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 350-356[artículo] A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments [texto impreso] / Yvonne M. Greene, Autor ; Pierre N. Tariot, Autor ; Heather Wishart, Autor . - 2023 . - pp. 350-356.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 350-356
Palabras clave: Trastornos cognitivos, Indanos - efectos adversos, Indios, Esclerosis múltiple, Agentes Nootrópicos, Piperidinas. Resumen: Cognitive dysfunction occurs in up to 65% of patients with multiple sclerosis (MS), but there is no effective treatment for the symptoms. The authors conducted a 12-week, open-pilot study to assess the efficacy and tolerability of donepezil HCl administered in patients with MS and cognitive impairment. Seventeen patients at a long-term care facility with Mini-Mental State Examination scores of ≤ 25 received 5 mg of donepezil HCl for a 4-week period, followed by 8 weeks of 10 mg of donepezil HCl. Link: ./index.php?lvl=notice_display&id=31194
Título : Longitudinal comparative study of risperidone and conventional neuroleptics for treating patients with schizophrenia Tipo de documento: texto impreso Autores: Roch Hugo Bouchard, Autor ; Chantal Mérette, Autor ; Emmanuelle Pourcher, Autor Fecha de publicación: 2023 Artículo en la página: pp. 95-304 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Enfermedad crónica, Abandono de pacientes, Risperidona, Esquizofrenia. Resumen: This study compared the long-term (12 months) effectiveness of risperidone (RP) with that of conventional neuroleptics (CNs) in a population with chronic schizophrenia who had shown suboptimal response to CNs. A randomized, open, parallel, multicenter design was used. One hundred eighty-four subjects meeting DSM-IV criteria for schizophrenia were randomly assigned to receive either RP or a CN, and 165 of them completed the follow-up. Link: ./index.php?lvl=notice_display&id=31195
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 95-304[artículo] Longitudinal comparative study of risperidone and conventional neuroleptics for treating patients with schizophrenia [texto impreso] / Roch Hugo Bouchard, Autor ; Chantal Mérette, Autor ; Emmanuelle Pourcher, Autor . - 2023 . - pp. 95-304.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 95-304
Palabras clave: Antipsicóticos, Enfermedad crónica, Abandono de pacientes, Risperidona, Esquizofrenia. Resumen: This study compared the long-term (12 months) effectiveness of risperidone (RP) with that of conventional neuroleptics (CNs) in a population with chronic schizophrenia who had shown suboptimal response to CNs. A randomized, open, parallel, multicenter design was used. One hundred eighty-four subjects meeting DSM-IV criteria for schizophrenia were randomly assigned to receive either RP or a CN, and 165 of them completed the follow-up. Link: ./index.php?lvl=notice_display&id=31195
Título : Risperidone for the treatment of cocaine dependence: randomized, double-blind trial Tipo de documento: texto impreso Autores: John Grabowski, Autor ; Howard Rhoades, Autor ; Peter Silverman, Autor Fecha de publicación: 2023 Artículo en la página: pp. 305-310 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Cocaína, Trastornos relacionados con la cocaína, Antagonistas de la dopamina, Abandono de pacientes, Psicoterapia, Risperidona. Resumen: A partial blockade of the multiple actions of cocaine is one strategy by which cocaine dependence may be treated. Risperidone, a 5-hydroxytryptamine and dopamine D2 antagonist, is an atypical antipsychotic and was a candidate medication for the treatment of cocaine dependence. One hundred ninety-three cocaine-dependent subjects were enrolled in a 12-week, randomized, double-blind, placebo-controlled trial. Link: ./index.php?lvl=notice_display&id=31196
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 305-310[artículo] Risperidone for the treatment of cocaine dependence: randomized, double-blind trial [texto impreso] / John Grabowski, Autor ; Howard Rhoades, Autor ; Peter Silverman, Autor . - 2023 . - pp. 305-310.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 305-310
Palabras clave: Cocaína, Trastornos relacionados con la cocaína, Antagonistas de la dopamina, Abandono de pacientes, Psicoterapia, Risperidona. Resumen: A partial blockade of the multiple actions of cocaine is one strategy by which cocaine dependence may be treated. Risperidone, a 5-hydroxytryptamine and dopamine D2 antagonist, is an atypical antipsychotic and was a candidate medication for the treatment of cocaine dependence. One hundred ninety-three cocaine-dependent subjects were enrolled in a 12-week, randomized, double-blind, placebo-controlled trial. Link: ./index.php?lvl=notice_display&id=31196
Título : Anticholinergic differences among patients receiving standard clinical doses of olanzapine or clozapine Tipo de documento: texto impreso Autores: K. N. R. Chengappa, Autor ; Bruce G. Pollock, Autor ; Haranath Parepally, Autor Fecha de publicación: 2023 Artículo en la página: pp. 311-316 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Atropina, Enfermedades del sistema nervioso autónomo, Antagonistas colinérgicos, Clozapina, Antagonistas muscarínicos, Pirenzepina, Trastornos psicóticos. Resumen: This study evaluated anticholinergic effects among patients with schizophrenia, schizoaffective disorder, or bipolar I disorder who were receiving either olanzapine (N = 12) or clozapine (N = 12) at standard clinical doses in a naturalistic setting. Serum anticholinergic levels were determined in adult male and female subjects using a radioreceptor binding assay. The Udvalg for Kliniske Undersogelser Scale was used to evaluate anticholinergic side effects clinically, and the Mini-Mental State Examination provided a global cognitive measure. Link: ./index.php?lvl=notice_display&id=31197
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 311-316[artículo] Anticholinergic differences among patients receiving standard clinical doses of olanzapine or clozapine [texto impreso] / K. N. R. Chengappa, Autor ; Bruce G. Pollock, Autor ; Haranath Parepally, Autor . - 2023 . - pp. 311-316.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 311-316
Palabras clave: Antipsicóticos, Atropina, Enfermedades del sistema nervioso autónomo, Antagonistas colinérgicos, Clozapina, Antagonistas muscarínicos, Pirenzepina, Trastornos psicóticos. Resumen: This study evaluated anticholinergic effects among patients with schizophrenia, schizoaffective disorder, or bipolar I disorder who were receiving either olanzapine (N = 12) or clozapine (N = 12) at standard clinical doses in a naturalistic setting. Serum anticholinergic levels were determined in adult male and female subjects using a radioreceptor binding assay. The Udvalg for Kliniske Undersogelser Scale was used to evaluate anticholinergic side effects clinically, and the Mini-Mental State Examination provided a global cognitive measure. Link: ./index.php?lvl=notice_display&id=31197
Título : Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with Tourette syndrome Tipo de documento: texto impreso Autores: David A. Flockhart, Autor ; Milou Daniel Drici, Autor ; Thomas Kerbusch, Autor Fecha de publicación: 2023 Artículo en la página: pp. 317-324 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Claritromicina, Muerte súbita, Electrocardiografía, Microsomas, Pimozida, Síndrome de Tourette. Resumen: The authors report in detail the case of a 27-year-old man who experienced sudden cardiac death 2 days after coprescription of the neuroleptic pimozide and the macrolide antibiotic clarithromycin after the documentation of a prolonged QT interval. To determine the prevalence of this interaction, the authors referred to the Spontaneous Reporting System of the Food and Drug Administration and identified one similar case in which clarithromycin was coprescribed with pimozide and sudden cardiac death occurred shortly thereafter. Link: ./index.php?lvl=notice_display&id=31198
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 317-324[artículo] Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with Tourette syndrome [texto impreso] / David A. Flockhart, Autor ; Milou Daniel Drici, Autor ; Thomas Kerbusch, Autor . - 2023 . - pp. 317-324.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 317-324
Palabras clave: Antipsicóticos, Claritromicina, Muerte súbita, Electrocardiografía, Microsomas, Pimozida, Síndrome de Tourette. Resumen: The authors report in detail the case of a 27-year-old man who experienced sudden cardiac death 2 days after coprescription of the neuroleptic pimozide and the macrolide antibiotic clarithromycin after the documentation of a prolonged QT interval. To determine the prevalence of this interaction, the authors referred to the Spontaneous Reporting System of the Food and Drug Administration and identified one similar case in which clarithromycin was coprescribed with pimozide and sudden cardiac death occurred shortly thereafter. Link: ./index.php?lvl=notice_display&id=31198
Título : Sudden death in patients receiving clozapine treatment: a preliminary investigation Tipo de documento: texto impreso Autores: Ilan Modai, Autor ; Shmuel Hirschmann, Autor ; Alla Rava, Autor Fecha de publicación: 2023 Artículo en la página: pp. 325-327 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Antipsicóticos, Clozapina, Muerte súbita, Israel, Suicidio. Resumen: The risk of sudden death during clozapine treatment is controversial. The authors present a review of sudden deaths that occurred at Sha'ar Menashe Mental Health Center between January 1991 and August 1997. The number of cases of deceased inpatients was retrieved from the hospital's computerized database and divided into three groups: sudden death, suicide, and disease-related death. Copies of mandatory reports of sudden death filed with the Ministry of Health were obtained, and the corresponding patient records were reviewed. Link: ./index.php?lvl=notice_display&id=31199
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 325-327[artículo] Sudden death in patients receiving clozapine treatment: a preliminary investigation [texto impreso] / Ilan Modai, Autor ; Shmuel Hirschmann, Autor ; Alla Rava, Autor . - 2023 . - pp. 325-327.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 325-327
Palabras clave: Antipsicóticos, Clozapina, Muerte súbita, Israel, Suicidio. Resumen: The risk of sudden death during clozapine treatment is controversial. The authors present a review of sudden deaths that occurred at Sha'ar Menashe Mental Health Center between January 1991 and August 1997. The number of cases of deceased inpatients was retrieved from the hospital's computerized database and divided into three groups: sudden death, suicide, and disease-related death. Copies of mandatory reports of sudden death filed with the Ministry of Health were obtained, and the corresponding patient records were reviewed. Link: ./index.php?lvl=notice_display&id=31199
Título : Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance Tipo de documento: texto impreso Autores: Steven M. Troy, Autor ; Irwin Lucki, Autor ; Mary A. Unruh, Autor Fecha de publicación: 2023 Artículo en la página: pp. 328-337 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Acetamidas, Hipnóticos y Sedantes, Aprendizaje - efectos del medicamento, Memoria, Recuerdo mental, Rendimiento psicomotor, Piridinas, Pirimidinas, Características sexuales. Resumen: Twenty-four healthy male and female subjects, who participated in this randomized, double-blind, crossover study, received single nighttime doses of zaleplon 10 mg (therapeutic dose), zaleplon 20 mg, zolpidem 10 mg (therapeutic dose), zolpidem 20 mg, triazolam 0.25 mg (positive control), and placebo. Subjective behavioral ratings and psychomotor tests were completed before and 1.25 and 8.25 hours after administration of the study drug. Link: ./index.php?lvl=notice_display&id=31200
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 328-337[artículo] Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance [texto impreso] / Steven M. Troy, Autor ; Irwin Lucki, Autor ; Mary A. Unruh, Autor . - 2023 . - pp. 328-337.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 328-337
Palabras clave: Acetamidas, Hipnóticos y Sedantes, Aprendizaje - efectos del medicamento, Memoria, Recuerdo mental, Rendimiento psicomotor, Piridinas, Pirimidinas, Características sexuales. Resumen: Twenty-four healthy male and female subjects, who participated in this randomized, double-blind, crossover study, received single nighttime doses of zaleplon 10 mg (therapeutic dose), zaleplon 20 mg, zolpidem 10 mg (therapeutic dose), zolpidem 20 mg, triazolam 0.25 mg (positive control), and placebo. Subjective behavioral ratings and psychomotor tests were completed before and 1.25 and 8.25 hours after administration of the study drug. Link: ./index.php?lvl=notice_display&id=31200
Título : Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam Tipo de documento: texto impreso Autores: Gary B. Kaplan, Autor ; David J. Greenblatt, Autor ; Bruce L. Ehrenberg, Autor Fecha de publicación: 2023 Artículo en la página: pp. 338-346 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Alprazolam, Ansiolíticos, Trastorno de pánico. Resumen: The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers. Subjects received orally administered placebo and alprazolam in a randomized, double-blind, single-dose crossover study. Link: ./index.php?lvl=notice_display&id=31201
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 338-346[artículo] Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam [texto impreso] / Gary B. Kaplan, Autor ; David J. Greenblatt, Autor ; Bruce L. Ehrenberg, Autor . - 2023 . - pp. 338-346.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 338-346
Palabras clave: Alprazolam, Ansiolíticos, Trastorno de pánico. Resumen: The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers. Subjects received orally administered placebo and alprazolam in a randomized, double-blind, single-dose crossover study. Link: ./index.php?lvl=notice_display&id=31201
Título : Single-dose pharmacokinetics of methylphenidate in cyp2d6 extensive and poor metabolizers Tipo de documento: texto impreso Autores: C. Lindsay DeVane, Autor ; John S. Markowitz, Autor ; Stanley W. Carson, Autor Fecha de publicación: 2023 Artículo en la página: pp. 347-349 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31202
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349[artículo] Single-dose pharmacokinetics of methylphenidate in cyp2d6 extensive and poor metabolizers [texto impreso] / C. Lindsay DeVane, Autor ; John S. Markowitz, Autor ; Stanley W. Carson, Autor . - 2023 . - pp. 347-349.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 347-349
Palabras clave: Estimulantes del sistema nervioso central, Citocromo P-450 CYP2D6, Espectrometría de masas, Metilfenidato. Resumen: Six adults phenotyped as either extensive (N = 4) or poor (N = 2) metabolizers for cytochrome P450 (CYP) 2D6 were given a 10-mg oral dose of methylphenidate (MPH) on two separate occasions with and without quinidine, a potent CYP2D6 inhibitor. Quinidine had no significant effect on the pharmacokinetics of either MPH or ritalinic acid, its major metabolite, in either group of CYP2D6 metabolizers. Link: ./index.php?lvl=notice_display&id=31202
Título : A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments Tipo de documento: texto impreso Autores: Yvonne M. Greene, Autor ; Pierre N. Tariot, Autor ; Heather Wishart, Autor Fecha de publicación: 2023 Artículo en la página: pp. 350-356 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastornos cognitivos, Indios, Esclerosis múltiple, Agentes nootrópicos, Piperidinas. Resumen: Cognitive dysfunction occurs in up to 65% of patients with multiple sclerosis (MS), but there is no effective treatment for the symptoms. The authors conducted a 12-week, open-pilot study to assess the efficacy and tolerability of donepezil HCl administered in patients with MS and cognitive impairment. Seventeen patients at a long-term care facility with Mini-Mental State Examination scores of ≤ 25 received 5 mg of donepezil HCl for a 4-week period, followed by 8 weeks of 10 mg of donepezil HCl. Link: ./index.php?lvl=notice_display&id=31203
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 350-356[artículo] A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments [texto impreso] / Yvonne M. Greene, Autor ; Pierre N. Tariot, Autor ; Heather Wishart, Autor . - 2023 . - pp. 350-356.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 3 (Junio) . - pp. 350-356
Palabras clave: Trastornos cognitivos, Indios, Esclerosis múltiple, Agentes nootrópicos, Piperidinas. Resumen: Cognitive dysfunction occurs in up to 65% of patients with multiple sclerosis (MS), but there is no effective treatment for the symptoms. The authors conducted a 12-week, open-pilot study to assess the efficacy and tolerability of donepezil HCl administered in patients with MS and cognitive impairment. Seventeen patients at a long-term care facility with Mini-Mental State Examination scores of ≤ 25 received 5 mg of donepezil HCl for a 4-week period, followed by 8 weeks of 10 mg of donepezil HCl. Link: ./index.php?lvl=notice_display&id=31203
