A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia / Irit Gil-Ad en European Neuropsychopharmacology, Año 2014 - Vol. 24 - No.3 (Marzo)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2014 - Vol. 24 - No.3 (Marzo) . - pp. 425-436 Título : A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia Tipo de documento: texto impreso Autores: Irit Gil-Ad, Autor ; Moshe Portnoy, Autor ; Igor Tarasenko, Autor Fecha de publicación: 2021 Artículo en la página: pp. 425-436 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Esquizofrenia, Receptor de N-metil-d-aspartato (NMDA-R), Glutamato, Antipsicótico, Síntomas positivos, Síntomas negativos Resumen: Schizophrenia is a chronic mental disorder related to hypo-functioning of glutamatergic neurotransmission. N-methyl-d-aspartate-receptor (NMDA-R) positive modulators were reported to reduce schizophrenia symptoms. Link: ./index.php?lvl=notice_display&id=27062 [artículo] A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia [texto impreso] / Irit Gil-Ad, Autor ; Moshe Portnoy, Autor ; Igor Tarasenko, Autor . - 2021 . - pp. 425-436. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.3 (Marzo) . - pp. 425-436 Palabras clave: Esquizofrenia, Receptor de N-metil-d-aspartato (NMDA-R), Glutamato, Antipsicótico, Síntomas positivos, Síntomas negativos Resumen: Schizophrenia is a chronic mental disorder related to hypo-functioning of glutamatergic neurotransmission. N-methyl-d-aspartate-receptor (NMDA-R) positive modulators were reported to reduce schizophrenia symptoms. Link: ./index.php?lvl=notice_display&id=27062

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