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[artículo]
| Título : |
Subject selection for the placebo- and comparator-controlled trials of neuroleptics in schizophrenia |
| Tipo de documento: |
texto impreso |
| Autores: |
Pavel Mohr, Autor ; Pál Czobor, Autor |
| Fecha de publicación: |
2023 |
| Artículo en la página: |
pp. 240-245 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
Antipsicóticos, Diseño de investigación, Esquizofrenia. |
| Resumen: |
It has been suggested that inclusion of a placebo treatment arm in controlled clinical trials might bias the selection of study subjects. Presumably, patients in the placebo-controlled studies are more stable, but there are no data available to support such an assumption. The authors tested the hypothesis in a set of randomized trials of neuroleptics in treating schizophrenia by comparing placebo-controlled (PCTs) and comparator-controlled trials (CCTs) in terms of basic patient characteristics. |
| Link: |
./index.php?lvl=notice_display&id=31221 |
in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 2 (Abril) . - pp. 240-245
[artículo] Subject selection for the placebo- and comparator-controlled trials of neuroleptics in schizophrenia [texto impreso] / Pavel Mohr, Autor ; Pál Czobor, Autor . - 2023 . - pp. 240-245. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in Journal of Clinical Psychopharmacology > Año 2000 - Vol. 20 - No. 2 (Abril) . - pp. 240-245
| Palabras clave: |
Antipsicóticos, Diseño de investigación, Esquizofrenia. |
| Resumen: |
It has been suggested that inclusion of a placebo treatment arm in controlled clinical trials might bias the selection of study subjects. Presumably, patients in the placebo-controlled studies are more stable, but there are no data available to support such an assumption. The authors tested the hypothesis in a set of randomized trials of neuroleptics in treating schizophrenia by comparing placebo-controlled (PCTs) and comparator-controlled trials (CCTs) in terms of basic patient characteristics. |
| Link: |
./index.php?lvl=notice_display&id=31221 |
|
