[artículo] 
inEuropean Neuropsychopharmacology > Año 2014 - Vol. 24 - No.8 (Agosto) . - pp. 1349-1361

Título :	Characterisation of the antidepressant properties of nitric oxide synthase inhibitors in the olfactory bulbectomised rat model of depression
Tipo de documento:	texto impreso
Autores:	Valentina Gigliucci, Autor ; Shane Gormley, Autor ; Sinead M. Gibney, Autor
Fecha de publicación:	2021
Artículo en la página:	pp. 1349-1361
Idioma :	Inglés (eng) Idioma original : Inglés (eng)
Palabras clave:	Óxido nítrico sintasa, Antidepresivo, Depresión, Rata bulbectomizada olfativa, Campo abierto, Imagen de resonancia magnética
Resumen:	Nitric oxide synthase (NOS) inhibitors possess antidepressant-like properties in preclinical tests and in the current investigation the brain penetrant NOS inhibitor Nω-nitro-l-arginine (l-NA) and the preferential inhibitor of neuronal NOS (nNOS) 1-(2-trifluoromethylphenyl) imidazole (TRIM) were assessed in the olfactory bulbectomised (OB) rat, a well-established animal model of depression.
Link:	./index.php?lvl=notice_display&id=26908

[artículo] Characterisation of the antidepressant properties of nitric oxide synthase inhibitors in the olfactory bulbectomised rat model of depression [texto impreso] / Valentina Gigliucci, Autor ; Shane Gormley, Autor ; Sinead M. Gibney, Autor . - 2021 . - pp. 1349-1361.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.8 (Agosto) . - pp. 1349-1361

Palabras clave:	Óxido nítrico sintasa, Antidepresivo, Depresión, Rata bulbectomizada olfativa, Campo abierto, Imagen de resonancia magnética
Resumen:	Nitric oxide synthase (NOS) inhibitors possess antidepressant-like properties in preclinical tests and in the current investigation the brain penetrant NOS inhibitor Nω-nitro-l-arginine (l-NA) and the preferential inhibitor of neuronal NOS (nNOS) 1-(2-trifluoromethylphenyl) imidazole (TRIM) were assessed in the olfactory bulbectomised (OB) rat, a well-established animal model of depression.
Link:	./index.php?lvl=notice_display&id=26908