[artículo]
| Título : |
A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice |
| Tipo de documento: |
texto impreso |
| Autores: |
Valentina Pastore, Autor ; Cristina Wasowski, Autor ; Josefina Higgs, Autor |
| Fecha de publicación: |
2021 |
| Artículo en la página: |
pp. 1405-1414 |
| Idioma : |
Inglés (eng) Idioma original : Inglés (eng) |
| Palabras clave: |
3-butil-5,5-dimetil-1,2,3-oxatiazolidin-4-ona-2,2-dióxido, Anticonvulsivo, Daño oxidativo, Antidepresivo, Veratrina |
| Resumen: |
Epilepsy is recognized as one of the most common and serious neurological disorder affecting 1–2% of the world׳s population. The present study demonstrates that systemic administration of 3-butyl-5,5-dimethyl-1,2,3-oxathiazolidine-4-one-2,2-dioxide (DIOXIDE), a synthetic compound bioisoster of trimethadione and phenytoin (classical anticonvulsants), |
| Link: |
./index.php?lvl=notice_display&id=26913 |
in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.8 (Agosto) . - pp. 1405-1414
[artículo] A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice [texto impreso] / Valentina Pastore, Autor ; Cristina Wasowski, Autor ; Josefina Higgs, Autor . - 2021 . - pp. 1405-1414. Idioma : Inglés ( eng) Idioma original : Inglés ( eng) in European Neuropsychopharmacology > Año 2014 - Vol. 24 - No.8 (Agosto) . - pp. 1405-1414
| Palabras clave: |
3-butil-5,5-dimetil-1,2,3-oxatiazolidin-4-ona-2,2-dióxido, Anticonvulsivo, Daño oxidativo, Antidepresivo, Veratrina |
| Resumen: |
Epilepsy is recognized as one of the most common and serious neurological disorder affecting 1–2% of the world׳s population. The present study demonstrates that systemic administration of 3-butyl-5,5-dimethyl-1,2,3-oxathiazolidine-4-one-2,2-dioxide (DIOXIDE), a synthetic compound bioisoster of trimethadione and phenytoin (classical anticonvulsants), |
| Link: |
./index.php?lvl=notice_display&id=26913 |
|
A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice en European Neuropsychopharmacology, Año 2014 - Vol. 24 - No.8 (Agosto)
