Artículos

Genetic origins of suicidality? A synopsis of genes in suicidal behaviours, with regard to evidence diversity, disorder specificity and neurodevelopmental brain transcriptomics / Marcus Sokolowski en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 1-11 Título : Genetic origins of suicidality? A synopsis of genes in suicidal behaviours, with regard to evidence diversity, disorder specificity and neurodevelopmental brain transcriptomics Tipo de documento: texto impreso Autores: Marcus Sokolowski, Autor ; Danuta Wasserman, Autor Fecha de publicación: 2021 Artículo en la página: pp. 1-11 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Suicidio, Comportamiento suicida, Neurodesarrollo, Transcriptómica, Cerebro, FFetal Resumen: With regard to suicidal behavior (SB) genetics, many novel genes have been implicated over the years, in particular by a variety of hypothesis-free genomic methods (e.g. GWAS and exome sequencing). Link: ./index.php?lvl=notice_display&id=26315 [artículo] Genetic origins of suicidality? A synopsis of genes in suicidal behaviours, with regard to evidence diversity, disorder specificity and neurodevelopmental brain transcriptomics [texto impreso] / Marcus Sokolowski, Autor ; Danuta Wasserman, Autor . - 2021 . - pp. 1-11. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 1-11 Palabras clave: Suicidio, Comportamiento suicida, Neurodesarrollo, Transcriptómica, Cerebro, FFetal Resumen: With regard to suicidal behavior (SB) genetics, many novel genes have been implicated over the years, in particular by a variety of hypothesis-free genomic methods (e.g. GWAS and exome sequencing). Link: ./index.php?lvl=notice_display&id=26315

Social interaction reward / Rana El Rawas en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 12-28 Título : Social interaction reward : A resilience approach to overcome vulnerability to drugs of abuse Tipo de documento: texto impreso Autores: Rana El Rawas, Autor ; Inês M. Amaral, Autor Fecha de publicación: 2021 Artículo en la página: pp. 12-28 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Drogadicción, Estrés, Interacción social, Resiliencia, Recompensa, Vulnerabilidad Resumen: Drug addiction is a multifactorial disorder resulting from the complex interaction between biological, environmental and drug-induced effects. Generally, stress is a well-known risk factor for the development of drug addiction and relapse. Link: ./index.php?lvl=notice_display&id=26316 [artículo] Social interaction reward : A resilience approach to overcome vulnerability to drugs of abuse [texto impreso] / Rana El Rawas, Autor ; Inês M. Amaral, Autor . - 2021 . - pp. 12-28. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 12-28 Palabras clave: Drogadicción, Estrés, Interacción social, Resiliencia, Recompensa, Vulnerabilidad Resumen: Drug addiction is a multifactorial disorder resulting from the complex interaction between biological, environmental and drug-induced effects. Generally, stress is a well-known risk factor for the development of drug addiction and relapse. Link: ./index.php?lvl=notice_display&id=26316

Welfare consequences for people diagnosed with attention deficit hyperactivity disorder (ADHD) / Poul Jennum en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 29-38 Título : Welfare consequences for people diagnosed with attention deficit hyperactivity disorder (ADHD) : A matched nationwide study in Denmark Tipo de documento: texto impreso Autores: Poul Jennum, Autor ; Lene Halling Hastrup, Autor ; Rikke Ibsen, Autor Fecha de publicación: 2021 Artículo en la página: pp. 29-38 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Trastorno por deficit de atencion e hiperactividad, Costos directos e indirectos, Cuidados en el hogar, Resultado funcional, Pareja Resumen: There is insufficient data regarding the excess direct and indirect costs associated with attention deficit hyperactivity disorder (ADHD). Using the Danish National Patient Registry (2002–2016), we identified 83,613 people of any age with a diagnosis of ADHD or who were using central-acting medication against ADHD (primarily methylphenidate,... Link: ./index.php?lvl=notice_display&id=26318 [artículo] Welfare consequences for people diagnosed with attention deficit hyperactivity disorder (ADHD) : A matched nationwide study in Denmark [texto impreso] / Poul Jennum, Autor ; Lene Halling Hastrup, Autor ; Rikke Ibsen, Autor . - 2021 . - pp. 29-38. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 29-38 Palabras clave: Trastorno por deficit de atencion e hiperactividad, Costos directos e indirectos, Cuidados en el hogar, Resultado funcional, Pareja Resumen: There is insufficient data regarding the excess direct and indirect costs associated with attention deficit hyperactivity disorder (ADHD). Using the Danish National Patient Registry (2002–2016), we identified 83,613 people of any age with a diagnosis of ADHD or who were using central-acting medication against ADHD (primarily methylphenidate,... Link: ./index.php?lvl=notice_display&id=26318

Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration / Li Qin en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Título : Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration Tipo de documento: texto impreso Autores: Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor Fecha de publicación: 2021 Artículo en la página: pp. 39-48 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319 [artículo] Regulation of melanocortin-4-receptor (MC4R) expression by SNP rs17066842 is dependent on glucose concentration [texto impreso] / Li Qin, Autor ; Arun Kumar Tiwari, Autor ; Clement C. Zai, Autor . - 2021 . - pp. 39-48. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 39-48 Palabras clave: MC4R rs17066842, EGR-1, Glucosa, Obesidad, Diabetes tipo 2, Organoides cerebrales Resumen: Melanocortin-4-receptor (MC4R) gene codes for a G-protein-coupled receptor that is highly expressed in the hypothalamus and involved in the regulation of appetite. Single-nucleotide polymorphisms (SNPs) in the MC4R gene region have been associated with obesity, type 2-diabetes (T2D) and with antipsychotic-induced weight gain. Link: ./index.php?lvl=notice_display&id=26319

Evaluation of causality between ADHD and Parkinson's disease / Gloria Hoi-Yee Li en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 49-63 Título : Evaluation of causality between ADHD and Parkinson's disease : mendelian randomization study Tipo de documento: texto impreso Autores: Gloria Hoi-Yee Li, Autor ; Grace Mengqin Ge, Autor ; Ching-Lung Cheung, Autor Fecha de publicación: 2021 Artículo en la página: pp. 49-63 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: TDAH, Enfermedad de Parkinson, Aleatorización mendeliana Resumen: In a retrospective cohort study, patients with attention-deficit hyperactivity disorder (ADHD) and psychostimulant prescription were associated with increased risk of Parkinson's disease (PD). It is unclear whether ADHD per se or psychostimulant prescription is associated with PD. Link: ./index.php?lvl=notice_display&id=26320 [artículo] Evaluation of causality between ADHD and Parkinson's disease : mendelian randomization study [texto impreso] / Gloria Hoi-Yee Li, Autor ; Grace Mengqin Ge, Autor ; Ching-Lung Cheung, Autor . - 2021 . - pp. 49-63. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 49-63 Palabras clave: TDAH, Enfermedad de Parkinson, Aleatorización mendeliana Resumen: In a retrospective cohort study, patients with attention-deficit hyperactivity disorder (ADHD) and psychostimulant prescription were associated with increased risk of Parkinson's disease (PD). It is unclear whether ADHD per se or psychostimulant prescription is associated with PD. Link: ./index.php?lvl=notice_display&id=26320

Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients / Robert L. Smith en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 64-69 Título : Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients Tipo de documento: texto impreso Autores: Robert L. Smith, Autor ; Marit Tveito, Autor ; Lennart Kyllesø, Autor Fecha de publicación: 2021 Artículo en la página: pp. 64-69 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Fármacos antipsicóticos, Incumplimiento, Polifarmacia, Monitorización de fármacos terapéuticos Resumen: Nonadherence to oral antipsychotic drugs is a major issue in clinical psychiatry giving rise to treatment failure. Further, polypharmacy is common in the treatment of psychotic disorders due to insufficient treatment effect during monotherapy. Link: ./index.php?lvl=notice_display&id=26321 [artículo] Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs – A study based on blood sample analyses from 24,239 patients [texto impreso] / Robert L. Smith, Autor ; Marit Tveito, Autor ; Lennart Kyllesø, Autor . - 2021 . - pp. 64-69. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 64-69 Palabras clave: Fármacos antipsicóticos, Incumplimiento, Polifarmacia, Monitorización de fármacos terapéuticos Resumen: Nonadherence to oral antipsychotic drugs is a major issue in clinical psychiatry giving rise to treatment failure. Further, polypharmacy is common in the treatment of psychotic disorders due to insufficient treatment effect during monotherapy. Link: ./index.php?lvl=notice_display&id=26321

Lentiviral-mediated up-regulation of let-7d microRNA decreases alcohol intake through down-regulating the dopamine D3 receptor / Amine Bahi en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 70-81 Título : Lentiviral-mediated up-regulation of let-7d microRNA decreases alcohol intake through down-regulating the dopamine D3 receptor Tipo de documento: texto impreso Autores: Amine Bahi, Autor ; Jean Luc Dreyer, Autor Fecha de publicación: 2021 Artículo en la página: pp. 70-81 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Consumo de alcohol, Receptor de dopamina D3, Etanol, Lentivirus, let-7d, LORR, Núcleo accumbens, Opción de dos botellas Resumen: Recent studies have shown that Lethal-7 (let-7) microRNA (miRNA) is involved in a wide range of psychiatric disorders such as anxiety, depression, schizophrenia, and cocaine addiction. Link: ./index.php?lvl=notice_display&id=26322 [artículo] Lentiviral-mediated up-regulation of let-7d microRNA decreases alcohol intake through down-regulating the dopamine D3 receptor [texto impreso] / Amine Bahi, Autor ; Jean Luc Dreyer, Autor . - 2021 . - pp. 70-81. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 70-81 Palabras clave: Consumo de alcohol, Receptor de dopamina D3, Etanol, Lentivirus, let-7d, LORR, Núcleo accumbens, Opción de dos botellas Resumen: Recent studies have shown that Lethal-7 (let-7) microRNA (miRNA) is involved in a wide range of psychiatric disorders such as anxiety, depression, schizophrenia, and cocaine addiction. Link: ./index.php?lvl=notice_display&id=26322

Social deprivation substantially changes multi-structural neurotransmitter signature of social interaction / Adam Hamed en European Neuropsychopharmacology, Año 2020 - Vol.37 (Agosto)

Público ISBD [artículo]  inEuropean Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 82-99 Título : Social deprivation substantially changes multi-structural neurotransmitter signature of social interaction : Glutamate concentration in amygdala and VTA as a key factor in social encounter-induced 50-kHz ultrasonic vocalization Tipo de documento: texto impreso Autores: Adam Hamed, Autor ; Miron Bartosz Kursa, Autor Fecha de publicación: 2021 Artículo en la página: pp. 82-99 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Dopamina, GABA, Glutamato, Glicina, Serotonina, Vocalización ultrasónica Resumen: Ultrasonic vocalizations are important for coordinating social behavior in rats. Examination of the neurochemical mechanisms that govern social behavior and ultrasonic vocalization emission is crucial for understanding the social impairments that occur in many neuropsychiatric disorders. Link: ./index.php?lvl=notice_display&id=26323 [artículo] Social deprivation substantially changes multi-structural neurotransmitter signature of social interaction : Glutamate concentration in amygdala and VTA as a key factor in social encounter-induced 50-kHz ultrasonic vocalization [texto impreso] / Adam Hamed, Autor ; Miron Bartosz Kursa, Autor . - 2021 . - pp. 82-99. Idioma : Inglés (eng) Idioma original : Inglés (eng) in European Neuropsychopharmacology > Año 2020 - Vol.37 (Agosto) . - pp. 82-99 Palabras clave: Dopamina, GABA, Glutamato, Glicina, Serotonina, Vocalización ultrasónica Resumen: Ultrasonic vocalizations are important for coordinating social behavior in rats. Examination of the neurochemical mechanisms that govern social behavior and ultrasonic vocalization emission is crucial for understanding the social impairments that occur in many neuropsychiatric disorders. Link: ./index.php?lvl=notice_display&id=26323