Artículos

Efficacy and safety of asenapine in a placebo- and haloperidol controlled trial in patients with acute exacerbation of schizophrenia / John M. Kane en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 106-115 Título : Efficacy and safety of asenapine in a placebo- and haloperidol controlled trial in patients with acute exacerbation of schizophrenia Tipo de documento: texto impreso Autores: John M. Kane, Autor ; Michael Cohen, Autor ; Jun Zhao, Autor Fecha de publicación: 2022 Artículo en la página: pp. 106-115 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Asenapina, Eficacia, Haloperidol, Seguridad, Esquizofrenia Resumen: Asenapine is approved by the Food and Drugs Administration in adults for acute treatment of schizophrenia or of manic or mixed episodes associated with bipolar I disorder with or without psychotic features. In a double-blind 6-week trial, 458 patients with acute schizophrenia were randomly assigned to fixed-dose treatment with asenapine at 5 mg twice daily (BID), asenapine at 10 mg BID, placebo, or haloperidol at 4 mg BID (to verify assay sensitivity). Link: ./index.php?lvl=notice_display&id=29455 [artículo] Efficacy and safety of asenapine in a placebo- and haloperidol controlled trial in patients with acute exacerbation of schizophrenia [texto impreso] / John M. Kane, Autor ; Michael Cohen, Autor ; Jun Zhao, Autor . - 2022 . - pp. 106-115. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 106-115 Palabras clave: Asenapina, Eficacia, Haloperidol, Seguridad, Esquizofrenia Resumen: Asenapine is approved by the Food and Drugs Administration in adults for acute treatment of schizophrenia or of manic or mixed episodes associated with bipolar I disorder with or without psychotic features. In a double-blind 6-week trial, 458 patients with acute schizophrenia were randomly assigned to fixed-dose treatment with asenapine at 5 mg twice daily (BID), asenapine at 10 mg BID, placebo, or haloperidol at 4 mg BID (to verify assay sensitivity). Link: ./index.php?lvl=notice_display&id=29455

Mrp1 polymorphisms associated with citalopram response in patients with major depression / Sung Hee Lee en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 116-125 Título : Mrp1 polymorphisms associated with citalopram response in patients with major depression Tipo de documento: texto impreso Autores: Sung Hee Lee, Autor ; Min Soo Lee, Autor ; Ji Hyun Lee, Autor Fecha de publicación: 2022 Artículo en la página: pp. 116-125 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: MRP1/ABCC1, Citalopram, Remisión, Trastorno depresivo mayor, Transportador ABC Resumen: Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variations in MRP1/ABCC1 and the therapeutic response to the antidepressant citalopram. Link: ./index.php?lvl=notice_display&id=29456 [artículo] Mrp1 polymorphisms associated with citalopram response in patients with major depression [texto impreso] / Sung Hee Lee, Autor ; Min Soo Lee, Autor ; Ji Hyun Lee, Autor . - 2022 . - pp. 116-125. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 116-125 Palabras clave: MRP1/ABCC1, Citalopram, Remisión, Trastorno depresivo mayor, Transportador ABC Resumen: Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variations in MRP1/ABCC1 and the therapeutic response to the antidepressant citalopram. Link: ./index.php?lvl=notice_display&id=29456

Parallel group placebo controlled trial of testosterone gel in men with major depressive disorder displaying an incomplete response to standard antidepressant treatment / Harrison G. Pope en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 126-134 Título : Parallel group placebo controlled trial of testosterone gel in men with major depressive disorder displaying an incomplete response to standard antidepressant treatment Tipo de documento: texto impreso Autores: Harrison G. Pope, Autor ; Revital Amiaz, Autor ; Brian P. Brennan, Autor Fecha de publicación: 2022 Artículo en la página: pp. 126-134 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Testosterona, Andrógenos, Masculino, Trastorno depresivo mayor, Inhibidor selectivo de la recaptación de serotonina, Potenciación Resumen: Exogenous testosterone therapy has psychotropic effects and has been proposed as an antidepressant augmentation strategy for depressed men. We sought to assess the antidepressant effects of testosterone augmentation of a serotonergic antidepressant in depressed, hypogonadal men. Link: ./index.php?lvl=notice_display&id=29457 [artículo] Parallel group placebo controlled trial of testosterone gel in men with major depressive disorder displaying an incomplete response to standard antidepressant treatment [texto impreso] / Harrison G. Pope, Autor ; Revital Amiaz, Autor ; Brian P. Brennan, Autor . - 2022 . - pp. 126-134. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 126-134 Palabras clave: Testosterona, Andrógenos, Masculino, Trastorno depresivo mayor, Inhibidor selectivo de la recaptación de serotonina, Potenciación Resumen: Exogenous testosterone therapy has psychotropic effects and has been proposed as an antidepressant augmentation strategy for depressed men. We sought to assess the antidepressant effects of testosterone augmentation of a serotonergic antidepressant in depressed, hypogonadal men. Link: ./index.php?lvl=notice_display&id=29457

Efficacy and safety of agomelatine in the treatment of major depressive disorder / John M. Zajecka en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 135-144 Título : Efficacy and safety of agomelatine in the treatment of major depressive disorder : A multicenter, randomized, double blind, placebo controlled trial Tipo de documento: texto impreso Autores: John M. Zajecka, Autor ; Alan F. Schatzberg, Autor ; Stephen M. Stahl, Autor Fecha de publicación: 2022 Artículo en la página: pp. 135-144 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Agomelatina, Antidepresivos, Trastorno depresivo mayor, Sueño Resumen: In this 8-week double-blind multicenter trial, we evaluated the efficacy and safety of 2 fixed doses of agomelatine in patients with moderate to severe major depressive disorder. Primary efficacy variable was the change in 17-item Hamilton Depression Rating Scale (HAM-D17) total score from baseline to week 8/end of treatment. Link: ./index.php?lvl=notice_display&id=29458 [artículo] Efficacy and safety of agomelatine in the treatment of major depressive disorder : A multicenter, randomized, double blind, placebo controlled trial [texto impreso] / John M. Zajecka, Autor ; Alan F. Schatzberg, Autor ; Stephen M. Stahl, Autor . - 2022 . - pp. 135-144. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 135-144 Palabras clave: Agomelatina, Antidepresivos, Trastorno depresivo mayor, Sueño Resumen: In this 8-week double-blind multicenter trial, we evaluated the efficacy and safety of 2 fixed doses of agomelatine in patients with moderate to severe major depressive disorder. Primary efficacy variable was the change in 17-item Hamilton Depression Rating Scale (HAM-D17) total score from baseline to week 8/end of treatment. Link: ./index.php?lvl=notice_display&id=29458

Quality of life and attention deficit hyperactivity disorder core symptoms / Rodrigo Escobar en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 145-151 Título : Quality of life and attention deficit hyperactivity disorder core symptoms : A pooled analysis of 5 non us atomoxetine clinical trials Tipo de documento: texto impreso Autores: Rodrigo Escobar, Autor ; Alexander Schacht, Autor ; Peter M. Wehmeier, Autor Fecha de publicación: 2022 Artículo en la página: pp. 145-151 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Calidad de vida, Atomoxetina, Perfil de Salud y Enfermedad Infantil, ADHD-RS Resumen: The objective of this pooled analysis was to correlate parameters related to quality of life with attention-deficit/hyperactivity disorder (ADHD) core symptoms analyzing data of 5 atomoxetine clinical trials in children and adolescents with ADHD. Link: ./index.php?lvl=notice_display&id=29459 [artículo] Quality of life and attention deficit hyperactivity disorder core symptoms : A pooled analysis of 5 non us atomoxetine clinical trials [texto impreso] / Rodrigo Escobar, Autor ; Alexander Schacht, Autor ; Peter M. Wehmeier, Autor . - 2022 . - pp. 145-151. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 145-151 Palabras clave: Calidad de vida, Atomoxetina, Perfil de Salud y Enfermedad Infantil, ADHD-RS Resumen: The objective of this pooled analysis was to correlate parameters related to quality of life with attention-deficit/hyperactivity disorder (ADHD) core symptoms analyzing data of 5 atomoxetine clinical trials in children and adolescents with ADHD. Link: ./index.php?lvl=notice_display&id=29459

Cocaine choice in humans during d amphetamine maintenance / Craig R. Rush en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 152-159 Título : Cocaine choice in humans during d amphetamine maintenance Tipo de documento: texto impreso Autores: Craig R. Rush, Autor ; William W. Stoops, Autor ; Rajkumar J. Sevak, Autor Fecha de publicación: 2022 Artículo en la página: pp. 152-159 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Humanos, Farmacoterapia, Terapia de reemplazo de agonistas, D-anfetamina, Cocaína, Elección, Refuerzo de drogas, Efectos subjetivos, Efectos fisiológicos Resumen: The results of preclinical laboratory experiments and clinical trials indicate that agonist replacements such as d-amphetamine may be a viable option for managing cocaine dependence. This study determined the effects of d-amphetamine maintenance on cocaine choice behavior in human participants. Link: ./index.php?lvl=notice_display&id=29460 [artículo] Cocaine choice in humans during d amphetamine maintenance [texto impreso] / Craig R. Rush, Autor ; William W. Stoops, Autor ; Rajkumar J. Sevak, Autor . - 2022 . - pp. 152-159. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 152-159 Palabras clave: Humanos, Farmacoterapia, Terapia de reemplazo de agonistas, D-anfetamina, Cocaína, Elección, Refuerzo de drogas, Efectos subjetivos, Efectos fisiológicos Resumen: The results of preclinical laboratory experiments and clinical trials indicate that agonist replacements such as d-amphetamine may be a viable option for managing cocaine dependence. This study determined the effects of d-amphetamine maintenance on cocaine choice behavior in human participants. Link: ./index.php?lvl=notice_display&id=29460

Long term benzodiazepine use and salivary cortisol / Leonie Manthey en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 160-168 Título : Long term benzodiazepine use and salivary cortisol : The netherlands study of depression and anxiety (nesda) Tipo de documento: texto impreso Autores: Leonie Manthey, Autor ; Erik J. Giltay, Autor ; Tineke van Veen, Autor Fecha de publicación: 2022 Artículo en la página: pp. 160-168 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Benzodiacepinas, Ansiolíticos, Cortisol, Eje HPA, Uso a largo plazo Resumen: As benzodiazepines (BZDs) have anxiolytic effects, it is expected that they influence the stress system. During short-term treatment, BZD use was found to suppress cortisol levels. However, little research has been done on the effects of long-term BZD administration on the hypothalamic-pituitary-adrenal (HPA) axis. Link: ./index.php?lvl=notice_display&id=29461 [artículo] Long term benzodiazepine use and salivary cortisol : The netherlands study of depression and anxiety (nesda) [texto impreso] / Leonie Manthey, Autor ; Erik J. Giltay, Autor ; Tineke van Veen, Autor . - 2022 . - pp. 160-168. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 160-168 Palabras clave: Benzodiacepinas, Ansiolíticos, Cortisol, Eje HPA, Uso a largo plazo Resumen: As benzodiazepines (BZDs) have anxiolytic effects, it is expected that they influence the stress system. During short-term treatment, BZD use was found to suppress cortisol levels. However, little research has been done on the effects of long-term BZD administration on the hypothalamic-pituitary-adrenal (HPA) axis. Link: ./index.php?lvl=notice_display&id=29461

Medication adherence in outpatients with severe mental disorders / Halldóra Jónsdóttir en Journal of Clinical Psychopharmacology, Año 2010 - Vol. 30 - No. 2 (Abril)

Público ISBD [artículo]  inJournal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 169-175 Título : Medication adherence in outpatients with severe mental disorders : Relation between self reports and serum level Tipo de documento: texto impreso Autores: Halldóra Jónsdóttir, Autor ; Stein Opjordsmoen, Autor ; Astrid B. Birkenaes, Autor Fecha de publicación: 2022 Artículo en la página: pp. 169-175 Idioma : Inglés (eng) Idioma original : Inglés (eng) Palabras clave: Adherencia a la medicación, Esquizofrenia, Trastorno bipolar, Autoinforme, Niveles séricos Resumen: Medication nonadherence in severe mental disorders is an important clinical issue, but estimates vary between studies. There is a need for valid self-reports for both research and clinical practice. This study examined the level of adherence to prescribed medication in outpatients with severe mental disorders and evaluated the validity of a simple self-report rating of adherence. Link: ./index.php?lvl=notice_display&id=29462 [artículo] Medication adherence in outpatients with severe mental disorders : Relation between self reports and serum level [texto impreso] / Halldóra Jónsdóttir, Autor ; Stein Opjordsmoen, Autor ; Astrid B. Birkenaes, Autor . - 2022 . - pp. 169-175. Idioma : Inglés (eng) Idioma original : Inglés (eng) in Journal of Clinical Psychopharmacology > Año 2010 - Vol. 30 - No. 2 (Abril) . - pp. 169-175 Palabras clave: Adherencia a la medicación, Esquizofrenia, Trastorno bipolar, Autoinforme, Niveles séricos Resumen: Medication nonadherence in severe mental disorders is an important clinical issue, but estimates vary between studies. There is a need for valid self-reports for both research and clinical practice. This study examined the level of adherence to prescribed medication in outpatients with severe mental disorders and evaluated the validity of a simple self-report rating of adherence. Link: ./index.php?lvl=notice_display&id=29462